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• W2103014915 abstract "The gamma-ray scintillation camera used in these studies was the Pho/Gamma manufactured by Nuclear-Chicago and adequately described by Anger (1–3) in a number of communications. This apparatus represents a distinct advantage over the conventional automatic scintillation scanner. The conventional scanner covers a given point briefly during its transverse, and a relatively high count rate is required to discriminate variations of concentration within an organ. On the other hand, the gamma camera sees each point continuously within its 9-in. diameter useful field and can be set to record as many total counts as are necessary to visualize these variations. For the usual dose of radioactive test agent employed in conventional automatic scintillation scanning the gamma camera can visualize the target in one-fifth to one-twentieth of the time of the conventional. Conversely, much smaller test doses and longer recording times can be used with the gamma camera, with reduced radiation exposure to the patient (4). A large dose of radioactive test agent rapidly injected into the antecubital vein of the arm can be followed through the thoracic vessels and heart, carotid arteries, abdominal aorta, and kidneys (5, 7) with serial five-second recordings from the time of injection, somewhat akin to angiography. The detector head of the scintillation camera is supported on a yolk, and the entire assembly has three degrees of freedom. This maneuverability permits the patient to be studied in either upright, recumbent, or inclined position, laterally or oblique, a feature not readily achieved in conventional automatic scanners. The following report reviews some of the applications of the gamma-ray scintillation camera to dynamic studies in patients. Method Technetium-99m (Tc99m) pertechnetate in doses between 5 and 10 millicuries yields a count rate sufficient to trace the bolus of an intravenous injection through the major arterial supply in the head and neck, thorax, and abdomen in serial fivesecond imaging intervals. The total-body exposure was estimated by Smith (8) to be about 130 millirads per 10 millicuries technetium-99m pertechnetate. A Velcro2 blood pressure cuff is inflated to a level between diastolic and systolic pressure for about one minute. The cuff is further inflated above systolic pressure, the Tc99m is injected into the antecubital vein, and the cuff is briskly released while it is still inflated (6). Results Thorax Figures 1, A-D are serial anteroposterior five-second exposures following a rapid intravenous injection of 7 millicuries Tc99m into the left antecubital vein. Figure 1, A (zero to five seconds) shows the bolus in the subclavian vein, innominate vein, superior vena cava, and entering the right side of the heart. In Figure 1, B (five to nine seconds) the Tc99m is also seen in the right atrium, right ventricle, pulmonary artery, and lungs. The Tc99m is distributed on both sides of the heart, lungs, and aorta in Figure 1, C (ten to fourteen seconds)." @default.
• W2103014915 created "2016-06-24" @default.
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• W2103014915 date "1966-04-01" @default.
• W2103014915 modified "2023-10-02" @default.
• W2103014915 title "Applications of the Gamma-Ray Scintillation Camera to Dynamic Studies in Man" @default.
• W2103014915 doi "https://doi.org/10.1148/86.4.634" @default.
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