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- W2103038265 endingPage "e0141044" @default.
- W2103038265 startingPage "e0141044" @default.
- W2103038265 abstract "The control of growth and development of all living organisms is a complex and dynamic process that requires the harmonious expression of numerous genes. Gene expression is mainly controlled by the activity of sequence-specific DNA binding proteins called transcription factors (TFs). Amongst the various classes of eukaryotic TFs, the MYB superfamily is one of the largest and most diverse, and it has considerably expanded in the plant kingdom. R2R3-MYBs have been extensively studied over the last 15 years. However, DNA-binding specificity has been characterized for only a small subset of these proteins. Therefore, one of the remaining challenges is the exhaustive characterization of the DNA-binding specificity of all R2R3-MYB proteins. In this study, we have developed a library of Arabidopsis thaliana R2R3-MYB open reading frames, whose DNA-binding activities were assayed in vivo (yeast one-hybrid experiments) with a pool of selected cis-regulatory elements. Altogether 1904 interactions were assayed leading to the discovery of specific patterns of interactions between the various R2R3-MYB subgroups and their DNA target sequences and to the identification of key features that govern these interactions. The present work provides a comprehensive in vivo analysis of R2R3-MYB binding activities that should help in predicting new DNA motifs and identifying new putative target genes for each member of this very large family of TFs. In a broader perspective, the generated data will help to better understand how TF interact with their target DNA sequences." @default.
- W2103038265 created "2016-06-24" @default.
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- W2103038265 date "2015-10-20" @default.
- W2103038265 modified "2023-10-12" @default.
- W2103038265 title "Analysis of the DNA-Binding Activities of the Arabidopsis R2R3-MYB Transcription Factor Family by One-Hybrid Experiments in Yeast" @default.
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- W2103038265 cites W1836238084 @default.
- W2103038265 cites W1963944394 @default.
- W2103038265 cites W1965172979 @default.
- W2103038265 cites W1974683004 @default.
- W2103038265 cites W1978050358 @default.
- W2103038265 cites W1979384872 @default.
- W2103038265 cites W1979573697 @default.
- W2103038265 cites W1980111781 @default.
- W2103038265 cites W1982424675 @default.
- W2103038265 cites W1983922522 @default.
- W2103038265 cites W1984044477 @default.
- W2103038265 cites W1987251971 @default.
- W2103038265 cites W1989871357 @default.
- W2103038265 cites W1991285367 @default.
- W2103038265 cites W2004795102 @default.
- W2103038265 cites W2004798786 @default.
- W2103038265 cites W2006688297 @default.
- W2103038265 cites W2008815882 @default.
- W2103038265 cites W2017022374 @default.
- W2103038265 cites W2024058212 @default.
- W2103038265 cites W2029274905 @default.
- W2103038265 cites W2033169664 @default.
- W2103038265 cites W2037928158 @default.
- W2103038265 cites W2039125155 @default.
- W2103038265 cites W2047501022 @default.
- W2103038265 cites W2048479722 @default.
- W2103038265 cites W2048506314 @default.
- W2103038265 cites W2050438321 @default.
- W2103038265 cites W2052545261 @default.
- W2103038265 cites W2053384550 @default.
- W2103038265 cites W2054141518 @default.
- W2103038265 cites W2062352708 @default.
- W2103038265 cites W2065623295 @default.
- W2103038265 cites W2065996794 @default.
- W2103038265 cites W2071809726 @default.
- W2103038265 cites W2072897152 @default.
- W2103038265 cites W2074380892 @default.
- W2103038265 cites W2086071959 @default.
- W2103038265 cites W2091512413 @default.
- W2103038265 cites W2092806862 @default.
- W2103038265 cites W2093093117 @default.
- W2103038265 cites W2094476648 @default.
- W2103038265 cites W2098586583 @default.
- W2103038265 cites W2099193109 @default.
- W2103038265 cites W2099779145 @default.
- W2103038265 cites W2103043453 @default.
- W2103038265 cites W2105883689 @default.
- W2103038265 cites W2106184652 @default.
- W2103038265 cites W2110390227 @default.
- W2103038265 cites W2113370839 @default.
- W2103038265 cites W2113575935 @default.
- W2103038265 cites W2115858602 @default.
- W2103038265 cites W2117275684 @default.
- W2103038265 cites W2119082311 @default.
- W2103038265 cites W2119118311 @default.
- W2103038265 cites W2121249247 @default.
- W2103038265 cites W2121665941 @default.
- W2103038265 cites W2124369430 @default.
- W2103038265 cites W2127322768 @default.
- W2103038265 cites W2128030779 @default.
- W2103038265 cites W2129439700 @default.
- W2103038265 cites W2129477920 @default.
- W2103038265 cites W2132656315 @default.
- W2103038265 cites W2133316034 @default.
- W2103038265 cites W2135128215 @default.
- W2103038265 cites W2141256702 @default.
- W2103038265 cites W2147135057 @default.
- W2103038265 cites W2147326988 @default.
- W2103038265 cites W2149098862 @default.
- W2103038265 cites W2158266834 @default.
- W2103038265 cites W2158561017 @default.
- W2103038265 cites W2158861601 @default.
- W2103038265 cites W2161490612 @default.
- W2103038265 cites W2162921898 @default.
- W2103038265 cites W2168513416 @default.
- W2103038265 cites W4230686 @default.
- W2103038265 doi "https://doi.org/10.1371/journal.pone.0141044" @default.
- W2103038265 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4613820" @default.