Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103067727> ?p ?o ?g. }
- W2103067727 endingPage "F179" @default.
- W2103067727 startingPage "F165" @default.
- W2103067727 abstract "The calcineurin homologous protein (CHP) belongs to an evolutionarily conserved Ca(2+)-binding protein subfamily. The CHP subfamily is composed of CHP1, CHP2, and CHP3, which in vertebrates share significant homology at the protein level with each other and between other Ca(2+)-binding proteins. The CHP structure consists of two globular domains containing from one to four EF-hand structural motifs (calcium-binding regions composed of two helixes, E and F, joined by a loop), the myristoylation, and nuclear export signals. These structural features are essential for the function of the three members of the CHP subfamily. Indeed, CHP1-CHP3 have multiple and diverse essential functions, ranging from the regulation of the plasma membrane Na(+)/H(+) exchanger protein function, to carrier vesicle trafficking and gene transcription. The diverse functions attributed to the CHP subfamily rendered an understanding of its action highly complex and often controversial. This review provides a comprehensive and organized examination of the properties and physiological roles of the CHP subfamily with a view to revealing a link between CHP diverse functions." @default.
- W2103067727 created "2016-06-24" @default.
- W2103067727 creator A5019092211 @default.
- W2103067727 creator A5023488815 @default.
- W2103067727 creator A5039509102 @default.
- W2103067727 creator A5050870740 @default.
- W2103067727 date "2012-07-15" @default.
- W2103067727 modified "2023-10-02" @default.
- W2103067727 title "Calcineurin homologous protein: a multifunctional Ca<sup>2+</sup>-binding protein family" @default.
- W2103067727 cites W1498832295 @default.
- W2103067727 cites W1504145802 @default.
- W2103067727 cites W1506279431 @default.
- W2103067727 cites W1511179741 @default.
- W2103067727 cites W1530129745 @default.
- W2103067727 cites W1536788210 @default.
- W2103067727 cites W1546275634 @default.
- W2103067727 cites W1586442162 @default.
- W2103067727 cites W1587918801 @default.
- W2103067727 cites W1599096372 @default.
- W2103067727 cites W1599277155 @default.
- W2103067727 cites W1617746883 @default.
- W2103067727 cites W1619162897 @default.
- W2103067727 cites W1670420367 @default.
- W2103067727 cites W1760396088 @default.
- W2103067727 cites W1858340774 @default.
- W2103067727 cites W1866995360 @default.
- W2103067727 cites W1892733044 @default.
- W2103067727 cites W191237385 @default.
- W2103067727 cites W1964344021 @default.
- W2103067727 cites W1965057959 @default.
- W2103067727 cites W1965608446 @default.
- W2103067727 cites W1966343281 @default.
- W2103067727 cites W1966606704 @default.
- W2103067727 cites W1969830914 @default.
- W2103067727 cites W1969897807 @default.
- W2103067727 cites W1970689030 @default.
- W2103067727 cites W1971909620 @default.
- W2103067727 cites W1973530388 @default.
- W2103067727 cites W1975038690 @default.
- W2103067727 cites W1975442641 @default.
- W2103067727 cites W1976965279 @default.
- W2103067727 cites W1977739714 @default.
- W2103067727 cites W1978829877 @default.
- W2103067727 cites W1980349044 @default.
- W2103067727 cites W1980531464 @default.
- W2103067727 cites W1984613650 @default.
- W2103067727 cites W1985922024 @default.
- W2103067727 cites W1986451296 @default.
- W2103067727 cites W1988029417 @default.
- W2103067727 cites W1989519336 @default.
- W2103067727 cites W1990829962 @default.
- W2103067727 cites W1992873835 @default.
- W2103067727 cites W2002644147 @default.
- W2103067727 cites W2004347894 @default.
- W2103067727 cites W2004624818 @default.
- W2103067727 cites W2005496979 @default.
- W2103067727 cites W2006234322 @default.
- W2103067727 cites W2006847543 @default.
- W2103067727 cites W2007651870 @default.
- W2103067727 cites W2008891635 @default.
- W2103067727 cites W2009776346 @default.
- W2103067727 cites W2012871721 @default.
- W2103067727 cites W2013275758 @default.
- W2103067727 cites W2015631023 @default.
- W2103067727 cites W2020784937 @default.
- W2103067727 cites W2021064499 @default.
- W2103067727 cites W2021420691 @default.
- W2103067727 cites W2025033557 @default.
- W2103067727 cites W2025100148 @default.
- W2103067727 cites W2027306618 @default.
- W2103067727 cites W2027935874 @default.
- W2103067727 cites W2028166231 @default.
- W2103067727 cites W2029870632 @default.
- W2103067727 cites W2032840486 @default.
- W2103067727 cites W2033076676 @default.
- W2103067727 cites W2035344027 @default.
- W2103067727 cites W2035844082 @default.
- W2103067727 cites W2036631473 @default.
- W2103067727 cites W2036865828 @default.
- W2103067727 cites W2038835746 @default.
- W2103067727 cites W2039191017 @default.
- W2103067727 cites W2040683778 @default.
- W2103067727 cites W2042294891 @default.
- W2103067727 cites W2043654227 @default.
- W2103067727 cites W2046767100 @default.
- W2103067727 cites W2049524204 @default.
- W2103067727 cites W2052366943 @default.
- W2103067727 cites W2055337993 @default.
- W2103067727 cites W2060315853 @default.
- W2103067727 cites W2060860482 @default.
- W2103067727 cites W2061272721 @default.
- W2103067727 cites W2062378730 @default.
- W2103067727 cites W2065228034 @default.
- W2103067727 cites W2066270106 @default.
- W2103067727 cites W2068547732 @default.
- W2103067727 cites W2069567942 @default.
- W2103067727 cites W2069939390 @default.
- W2103067727 cites W2073411380 @default.