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- W2103089706 startingPage "108" @default.
- W2103089706 abstract "Atrial fibrillation (AF) is the most potent common risk factor for ischemic stroke. The number of Americans with nonvalvular AF is expected to increase markedly over the next several decades, making AF-related stroke an important public health concern. Given the individual and societal burden associated with AF-related stroke, efforts to identify and implement efficacious and acceptably safe therapeutic stroke prevention strategies are paramount. This article reviews the existing randomized trial evidence supporting the efficacy of oral vitamin K antagonists (ie, warfarin) or aspirin for preventing thromboembolism in AF, as well as completed and ongoing studies exploring novel antithrombotic agents including the oral direct thrombin inhibitor, ximelagatran, other antiplatelet agents (eg, clopidogrel), factor Xa inhibitors, and other pharmacological agents and additional therapeutic approaches such as mechanical devices and surgical procedures to obliterate the left atrial appendage." @default.
- W2103089706 created "2016-06-24" @default.
- W2103089706 creator A5008046120 @default.
- W2103089706 creator A5020290782 @default.
- W2103089706 creator A5055666587 @default.
- W2103089706 date "2005-09-01" @default.
- W2103089706 modified "2023-10-14" @default.
- W2103089706 title "Antithrombotic Therapy for Stroke Prevention in Atrial Fibrillation" @default.
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- W2103089706 doi "https://doi.org/10.1016/j.pcad.2005.06.007" @default.
- W2103089706 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16253651" @default.
- W2103089706 hasPublicationYear "2005" @default.
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