FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103097977> ?p ?o ?g. }

• W2103097977 endingPage "4003" @default.
• W2103097977 startingPage "3997" @default.
• W2103097977 abstract "Infection with certain human papillomavirus (HPV) genotypes is the most important risk factor related with cervical cancer. The objective of the present study was to investigate the prevalence of HPV infection, the distribution of HPV genotypes and HPV E6/E7 oncogene mRNA expression in Turkish women with different cervical cytological findings in Mersin province, Southern Turkey.A total of 476 cytological samples belonging to women with normal and abnormal cervical Pap smears were enrolled in the study. For the detection and genotyping assay, a PCR/direct cycle sequencing approach was used. E6/E7 mRNA expression of HPV-16, 18, 31, 33, and 45 was determined by type-specific real-time NASBA assay (NucliSENS EasyQ(®)HPV v1.1).Of the 476 samples, 106 (22.3%) were found to be positive for HPV DNA by PCR. The presence of HPV was significantly more common (p<0.001) in HSIL (6/8, 75%) when compared with LSIL (6/14, 42.9%), ASC-US (22/74, 29.7%) and normal cytology (72/380, 18.9%). The most prevalent genotypes were, in descending order of frequency, HPV genotype 66 (22.6%), 16 (20.8%), 6 (14.2%), 31 (11.3%), 53 (5.7%), and 83 (4.7%). HPV E6/E7 oncogene mRNA positivity (12/476, 2.5%) was lower than DNA positivity (38/476, 7.9%).Our data present a wide distribution of HPV genotypes in the analyzed population. HPV genotypes 66, 16, 6, 31, 53 and 83 were the predominant types and most of them were potential carcinogenic types. Because of the differences between HPV E6/E7 mRNA and DNA positivity, further studies are required to test the role of mRNA testing in the triage of women with abnormal cervical cytology or follow up of HPV DNA positive and cytology negative. These epidemiological data will be important to determine the future impact of vaccination on HPV infected women in our region." @default.
• W2103097977 created "2016-06-24" @default.
• W2103097977 creator A5010441792 @default.
• W2103097977 creator A5012630433 @default.
• W2103097977 creator A5028906467 @default.
• W2103097977 creator A5032633348 @default.
• W2103097977 creator A5054076785 @default.
• W2103097977 creator A5067711266 @default.
• W2103097977 creator A5079616087 @default.
• W2103097977 creator A5079681869 @default.
• W2103097977 creator A5091311915 @default.
• W2103097977 date "2014-05-15" @default.
• W2103097977 modified "2023-10-16" @default.
• W2103097977 title "Human Papillomavirus Genotype Distribution and E6/E7 Oncogene Expression in Turkish Women with Cervical Cytological Findings" @default.
• W2103097977 cites W1964927845 @default.
• W2103097977 cites W1970633477 @default.
• W2103097977 cites W1980406533 @default.
• W2103097977 cites W1987072732 @default.
• W2103097977 cites W1993656989 @default.
• W2103097977 cites W1997836635 @default.
• W2103097977 cites W2007655160 @default.
• W2103097977 cites W2020386919 @default.
• W2103097977 cites W2020573981 @default.
• W2103097977 cites W2033837363 @default.
• W2103097977 cites W2055336634 @default.
• W2103097977 cites W2068600075 @default.
• W2103097977 cites W2068965703 @default.
• W2103097977 cites W2073426615 @default.
• W2103097977 cites W2086149022 @default.
• W2103097977 cites W2101196984 @default.
• W2103097977 cites W2109289495 @default.
• W2103097977 cites W2115518823 @default.
• W2103097977 cites W2126091370 @default.
• W2103097977 cites W2129307369 @default.
• W2103097977 cites W2131870878 @default.
• W2103097977 cites W2139349670 @default.
• W2103097977 cites W2140771141 @default.
• W2103097977 cites W2145905076 @default.
• W2103097977 cites W2148581258 @default.
• W2103097977 cites W2156657350 @default.
• W2103097977 cites W2162290128 @default.
• W2103097977 cites W2162954621 @default.
• W2103097977 cites W2170385036 @default.
• W2103097977 cites W2170454093 @default.
• W2103097977 cites W2199462906 @default.
• W2103097977 cites W2971590513 @default.
• W2103097977 doi "https://doi.org/10.7314/apjcp.2014.15.9.3997" @default.
• W2103097977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24935586" @default.
• W2103097977 hasPublicationYear "2014" @default.
• W2103097977 type Work @default.
• W2103097977 sameAs 2103097977 @default.
• W2103097977 citedByCount "17" @default.
• W2103097977 countsByYear W21030979772014 @default.
• W2103097977 countsByYear W21030979772015 @default.
• W2103097977 countsByYear W21030979772016 @default.
• W2103097977 countsByYear W21030979772017 @default.
• W2103097977 countsByYear W21030979772018 @default.
• W2103097977 countsByYear W21030979772019 @default.
• W2103097977 countsByYear W21030979772021 @default.
• W2103097977 countsByYear W21030979772022 @default.
• W2103097977 crossrefType "journal-article" @default.
• W2103097977 hasAuthorship W2103097977A5010441792 @default.
• W2103097977 hasAuthorship W2103097977A5012630433 @default.
• W2103097977 hasAuthorship W2103097977A5028906467 @default.
• W2103097977 hasAuthorship W2103097977A5032633348 @default.
• W2103097977 hasAuthorship W2103097977A5054076785 @default.
• W2103097977 hasAuthorship W2103097977A5067711266 @default.
• W2103097977 hasAuthorship W2103097977A5079616087 @default.
• W2103097977 hasAuthorship W2103097977A5079681869 @default.
• W2103097977 hasAuthorship W2103097977A5091311915 @default.
• W2103097977 hasBestOaLocation W21030979771 @default.
• W2103097977 hasConcept C104317684 @default.
• W2103097977 hasConcept C121608353 @default.
• W2103097977 hasConcept C126322002 @default.
• W2103097977 hasConcept C135763542 @default.
• W2103097977 hasConcept C143998085 @default.
• W2103097977 hasConcept C159047783 @default.
• W2103097977 hasConcept C18823058 @default.
• W2103097977 hasConcept C2778220009 @default.
• W2103097977 hasConcept C2778580637 @default.
• W2103097977 hasConcept C2778817970 @default.
• W2103097977 hasConcept C2781018059 @default.
• W2103097977 hasConcept C2908647359 @default.
• W2103097977 hasConcept C29456083 @default.
• W2103097977 hasConcept C29537977 @default.
• W2103097977 hasConcept C2994532551 @default.
• W2103097977 hasConcept C31467283 @default.
• W2103097977 hasConcept C54355233 @default.
• W2103097977 hasConcept C71924100 @default.
• W2103097977 hasConcept C86803240 @default.
• W2103097977 hasConcept C99454951 @default.
• W2103097977 hasConceptScore W2103097977C104317684 @default.
• W2103097977 hasConceptScore W2103097977C121608353 @default.
• W2103097977 hasConceptScore W2103097977C126322002 @default.
• W2103097977 hasConceptScore W2103097977C135763542 @default.
• W2103097977 hasConceptScore W2103097977C143998085 @default.
• W2103097977 hasConceptScore W2103097977C159047783 @default.
• W2103097977 hasConceptScore W2103097977C18823058 @default.

• next