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- W2103126238 abstract "A Candida albicans mitochondrial ribosomal protein S9 (MRPS9 ) cDNA was identified in a screen for sequences whose expression induce galactose lethality in Saccharomyces cerevisiae. MRPS9 appears to encode a protein of 346 amino acids with an N-terminal mitochondrial targeting sequence and an internal S9 signature that is conserved amongst eukaryotic mitochondrial and prokaryotic ribosomal protein S9 sequences. Expression of a GAL1–CaMRPS9 fusion in S. cerevisiae caused the slow development of a galactose-negative phenotype upon repeated subculturing, and this correlated with an increased frequency of petite mutant formation. Therefore, over-expression of CaMRPS9 interferes with S. cerevisiae mitochondrial function, which accounts for the inhibition of growth on galactose. The sequence has been entered in the EMBL data library under Accession Number AF067962. Copyright © 1999 John Wiley & Sons, Ltd." @default.
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- W2103126238 date "1999-01-30" @default.
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- W2103126238 title "Over-expression ofcandida albicans mitochondrial ribosomal protein S9 (MrpS9p) disturbs mitochondrial function inSaccharomyces cerevisiae" @default.
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- W2103126238 doi "https://doi.org/10.1002/(sici)1097-0061(19990130)15:2<139::aid-yea347>3.0.co;2-5" @default.
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