FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103128963> ?p ?o ?g. }

• W2103128963 endingPage "561" @default.
• W2103128963 startingPage "561" @default.
• W2103128963 abstract "<h3>Objective</h3> To describe the initial pediatric experience with intralesional bevacizumab (Avastin) treatment for children with severe, recurrent respiratory papilloma (RRP). <h3>Design</h3> Retrospective medical chart review. <h3>Setting</h3> Tertiary care multidisciplinary aerodigestive center. <h3>Patients</h3> Three children, aged 3 to 6 years, with severe RRP requiring more than 4 operative interventions in 1 year whose parents (or legal guardians) consented to adjuvant treatment with intralesional bevacizumab. <h3>Intervention</h3> All 3 children were treated as follows: surgical debridement with a microdebrider, pulsed potassium titanyl phosphate laser treatments, and adjuvant intralesional injections with bevacizumab (1.25 mg total). <h3>Main Outcome Measures</h3> Time interval between operative interventions, Derkay severity scale for RRP, and pediatric voice-related quality of life (PVRQOL) scores. <h3>Results</h3> All 3 children demonstrated increased time between operative interventions. Two children had a substantial decrease in their Derkay score and improved PVRQOL scores. One child, although time between operative interventions improved, did not have any change in Derkay score and required further adjuvant therapy. <h3>Conclusions</h3> Injectable bevacizumab appears to show some efficacy in prolonging the time between treatments and therefore reducing the number of treatments per year in children with severe RRP. However, before any meaningful conclusions can be drawn, further studies must be conducted in the form of head-to-head trials looking specifically at the issues of time between treatment intervals, efficacy of one adjunct over another, vocal outcomes, and whether several adjunctive treatments confer advantage over 1 treatment. In-depth and careful informed consent is mandatory for these studies so that parents are aware of the risks and benefits (known and unknown) before such individualized decisions are made." @default.
• W2103128963 created "2016-06-24" @default.
• W2103128963 creator A5053003046 @default.
• W2103128963 creator A5088847544 @default.
• W2103128963 date "2010-06-21" @default.
• W2103128963 modified "2023-10-02" @default.
• W2103128963 title "Use of 532-nm Pulsed Potassium Titanyl Phosphate Laser and Adjuvant Intralesional Bevacizumab for Aggressive Respiratory Papillomatosis in Children" @default.
• W2103128963 cites W1966278145 @default.
• W2103128963 cites W1968175271 @default.
• W2103128963 cites W1971284059 @default.
• W2103128963 cites W1976024994 @default.
• W2103128963 cites W1983797430 @default.
• W2103128963 cites W1986433691 @default.
• W2103128963 cites W1993271840 @default.
• W2103128963 cites W2005291098 @default.
• W2103128963 cites W2007351636 @default.
• W2103128963 cites W2007779260 @default.
• W2103128963 cites W2010392988 @default.
• W2103128963 cites W2011108910 @default.
• W2103128963 cites W2016006753 @default.
• W2103128963 cites W2022857499 @default.
• W2103128963 cites W2023926971 @default.
• W2103128963 cites W2024365416 @default.
• W2103128963 cites W2027550584 @default.
• W2103128963 cites W2030288291 @default.
• W2103128963 cites W2044752008 @default.
• W2103128963 cites W2047936074 @default.
• W2103128963 cites W2057844361 @default.
• W2103128963 cites W2060942743 @default.
• W2103128963 cites W2071712331 @default.
• W2103128963 cites W2074096046 @default.
• W2103128963 cites W2093759117 @default.
• W2103128963 cites W2101084400 @default.
• W2103128963 cites W2111047399 @default.
• W2103128963 cites W2114043445 @default.
• W2103128963 cites W2122595579 @default.
• W2103128963 cites W2123045921 @default.
• W2103128963 cites W2140594985 @default.
• W2103128963 cites W2142693543 @default.
• W2103128963 cites W2147914006 @default.
• W2103128963 cites W2150766933 @default.
• W2103128963 cites W2152423545 @default.
• W2103128963 cites W2159806677 @default.
• W2103128963 cites W2165765234 @default.
• W2103128963 cites W2171162544 @default.
• W2103128963 cites W2171864938 @default.
• W2103128963 cites W2404282470 @default.
• W2103128963 cites W2413591585 @default.
• W2103128963 doi "https://doi.org/10.1001/archoto.2010.81" @default.
• W2103128963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20566906" @default.
• W2103128963 hasPublicationYear "2010" @default.
• W2103128963 type Work @default.
• W2103128963 sameAs 2103128963 @default.
• W2103128963 citedByCount "44" @default.
• W2103128963 countsByYear W21031289632012 @default.
• W2103128963 countsByYear W21031289632013 @default.
• W2103128963 countsByYear W21031289632014 @default.
• W2103128963 countsByYear W21031289632015 @default.
• W2103128963 countsByYear W21031289632016 @default.
• W2103128963 countsByYear W21031289632017 @default.
• W2103128963 countsByYear W21031289632018 @default.
• W2103128963 countsByYear W21031289632019 @default.
• W2103128963 countsByYear W21031289632020 @default.
• W2103128963 countsByYear W21031289632021 @default.
• W2103128963 countsByYear W21031289632022 @default.
• W2103128963 countsByYear W21031289632023 @default.
• W2103128963 crossrefType "journal-article" @default.
• W2103128963 hasAuthorship W2103128963A5053003046 @default.
• W2103128963 hasAuthorship W2103128963A5088847544 @default.
• W2103128963 hasConcept C118552586 @default.
• W2103128963 hasConcept C126322002 @default.
• W2103128963 hasConcept C141071460 @default.
• W2103128963 hasConcept C159110408 @default.
• W2103128963 hasConcept C27415008 @default.
• W2103128963 hasConcept C2776694085 @default.
• W2103128963 hasConcept C2777802072 @default.
• W2103128963 hasConcept C2777863537 @default.
• W2103128963 hasConcept C2779951463 @default.
• W2103128963 hasConcept C2780474809 @default.
• W2103128963 hasConcept C2910019179 @default.
• W2103128963 hasConcept C71924100 @default.
• W2103128963 hasConceptScore W2103128963C118552586 @default.
• W2103128963 hasConceptScore W2103128963C126322002 @default.
• W2103128963 hasConceptScore W2103128963C141071460 @default.
• W2103128963 hasConceptScore W2103128963C159110408 @default.
• W2103128963 hasConceptScore W2103128963C27415008 @default.
• W2103128963 hasConceptScore W2103128963C2776694085 @default.
• W2103128963 hasConceptScore W2103128963C2777802072 @default.
• W2103128963 hasConceptScore W2103128963C2777863537 @default.
• W2103128963 hasConceptScore W2103128963C2779951463 @default.
• W2103128963 hasConceptScore W2103128963C2780474809 @default.
• W2103128963 hasConceptScore W2103128963C2910019179 @default.
• W2103128963 hasConceptScore W2103128963C71924100 @default.
• W2103128963 hasIssue "6" @default.
• W2103128963 hasLocation W21031289631 @default.
• W2103128963 hasLocation W21031289632 @default.
• W2103128963 hasOpenAccess W2103128963 @default.
• W2103128963 hasPrimaryLocation W21031289631 @default.

• next