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- W2103134476 abstract "Carcinogens injected into the excretory canal of submandibular gland of Donryu rats revealed the following histologic changes in salivary glands. 20-Methylcholanthrene induced squamous cell metaplasia, fibrosis in the early stages, and benign lymphoepithelial lesion-like pattern after 3 months. Dense hyalinization occurred after 4-5 months with so-called mixed tumor-like pattern. In the later stages epidermoid carcinoma and fibrosarcoma were observed. 9, 10-Dimethylbenzanthracene caused degenerative change, metaplasia, fibrosis and cell infiltration, and later carcinoma and sarcoma appeared at a high rate. 4-Nitroquinoline-N-oxide led to dense hyalinization and so-called mixed tumor-like pattern was observed in many specimens. N-nitroso-N-methyl urethane and N-methyl-N-nitroso-N'-nitroguanidine revealed metaplastic changes, fibrosis and lymphoid infiltration. Scarlet red induced remarkable infiltration and aggregation of lymphoid cells, showing benign lymphoepithelial lesion-like pattern." @default.
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- W2103134476 date "1975-01-01" @default.
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- W2103134476 title "HISTOLOGICAL CHANGES IN THE SUBMANDIBULAR GLANDS OF RATS AFTER INTRADUCTAL INJECTION OF CHEMICAL CARCINOGENS" @default.
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- W2103134476 doi "https://doi.org/10.1111/j.1440-1827.1975.tb00146.x" @default.
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