FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103138314> ?p ?o ?g. }

• W2103138314 endingPage "2091" @default.
• W2103138314 startingPage "2077" @default.
• W2103138314 abstract "DNA renaturation kinetics was used to examine the relative accessibility of various regions of the Tetrahymena ribosomal RNA gene (rDNA) chromatin to micrococcal nuclease. In nuclei from cells active in rRNA transcription, the transcribed region of the rDNA chromatin was as much as 5-fold more accessible than the average of the total chromatin. As few as 20% inactive genes in the population could have accounted for all of the hybridization, so the transcribed region of the active units may be totally unprotected from nuclease degradation. The terminal non-transcribed spacer downstream from the transcription unit was also preferentially digested, but to a smaller degree. The central non-transcribed spacer was degraded to the same extent as total chromatin after a high degree of nuclease digestion. In nuclei from starved cells, which have 96% reduced rRNA transcription, the transcribed and terminal spacer regions of the rDNA were again more accessible than the total chromatin from the same nuclei, but the difference did not exceed 2-fold. We conclude that transcriptional activation is accompanied by major changes in the structure of the ribosomal gene chromatin, and that the extent and/or type of structural alteration differs in each functionally defined region of the rDNA." @default.
• W2103138314 created "2016-06-24" @default.
• W2103138314 creator A5017573996 @default.
• W2103138314 creator A5070993516 @default.
• W2103138314 date "1983-01-01" @default.
• W2103138314 modified "2023-09-26" @default.
• W2103138314 title "Transcribed and non-transcribed regions ofTetrahymenaribosomal gene chromatin have different accessibilities to micrococcal nuclease" @default.
• W2103138314 cites W1131804799 @default.
• W2103138314 cites W1855011056 @default.
• W2103138314 cites W1968377491 @default.
• W2103138314 cites W1981625337 @default.
• W2103138314 cites W1985411871 @default.
• W2103138314 cites W1992798832 @default.
• W2103138314 cites W1995218232 @default.
• W2103138314 cites W1996773386 @default.
• W2103138314 cites W1998394617 @default.
• W2103138314 cites W2015866983 @default.
• W2103138314 cites W2016638271 @default.
• W2103138314 cites W2032536951 @default.
• W2103138314 cites W2036390512 @default.
• W2103138314 cites W2042543706 @default.
• W2103138314 cites W2043915712 @default.
• W2103138314 cites W2050327073 @default.
• W2103138314 cites W2056063068 @default.
• W2103138314 cites W2065896526 @default.
• W2103138314 cites W2078825043 @default.
• W2103138314 cites W2085182051 @default.
• W2103138314 cites W2088328955 @default.
• W2103138314 cites W2091738072 @default.
• W2103138314 cites W2095325933 @default.
• W2103138314 cites W2103555537 @default.
• W2103138314 cites W2164844546 @default.
• W2103138314 cites W2167885697 @default.
• W2103138314 cites W2399843448 @default.
• W2103138314 doi "https://doi.org/10.1093/nar/11.7.2077" @default.
• W2103138314 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/325863" @default.
• W2103138314 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6300792" @default.
• W2103138314 hasPublicationYear "1983" @default.
• W2103138314 type Work @default.
• W2103138314 sameAs 2103138314 @default.
• W2103138314 citedByCount "15" @default.
• W2103138314 countsByYear W21031383142013 @default.
• W2103138314 crossrefType "journal-article" @default.
• W2103138314 hasAuthorship W2103138314A5017573996 @default.
• W2103138314 hasAuthorship W2103138314A5070993516 @default.
• W2103138314 hasBestOaLocation W21031383142 @default.
• W2103138314 hasConcept C101762097 @default.
• W2103138314 hasConcept C104317684 @default.
• W2103138314 hasConcept C116029586 @default.
• W2103138314 hasConcept C138885662 @default.
• W2103138314 hasConcept C139024627 @default.
• W2103138314 hasConcept C144024400 @default.
• W2103138314 hasConcept C149923435 @default.
• W2103138314 hasConcept C150194340 @default.
• W2103138314 hasConcept C153911025 @default.
• W2103138314 hasConcept C155794727 @default.
• W2103138314 hasConcept C179926584 @default.
• W2103138314 hasConcept C182614070 @default.
• W2103138314 hasConcept C207812311 @default.
• W2103138314 hasConcept C2908647359 @default.
• W2103138314 hasConcept C41895202 @default.
• W2103138314 hasConcept C54355233 @default.
• W2103138314 hasConcept C67905577 @default.
• W2103138314 hasConcept C83640560 @default.
• W2103138314 hasConcept C84772758 @default.
• W2103138314 hasConcept C86803240 @default.
• W2103138314 hasConcept C90132467 @default.
• W2103138314 hasConceptScore W2103138314C101762097 @default.
• W2103138314 hasConceptScore W2103138314C104317684 @default.
• W2103138314 hasConceptScore W2103138314C116029586 @default.
• W2103138314 hasConceptScore W2103138314C138885662 @default.
• W2103138314 hasConceptScore W2103138314C139024627 @default.
• W2103138314 hasConceptScore W2103138314C144024400 @default.
• W2103138314 hasConceptScore W2103138314C149923435 @default.
• W2103138314 hasConceptScore W2103138314C150194340 @default.
• W2103138314 hasConceptScore W2103138314C153911025 @default.
• W2103138314 hasConceptScore W2103138314C155794727 @default.
• W2103138314 hasConceptScore W2103138314C179926584 @default.
• W2103138314 hasConceptScore W2103138314C182614070 @default.
• W2103138314 hasConceptScore W2103138314C207812311 @default.
• W2103138314 hasConceptScore W2103138314C2908647359 @default.
• W2103138314 hasConceptScore W2103138314C41895202 @default.
• W2103138314 hasConceptScore W2103138314C54355233 @default.
• W2103138314 hasConceptScore W2103138314C67905577 @default.
• W2103138314 hasConceptScore W2103138314C83640560 @default.
• W2103138314 hasConceptScore W2103138314C84772758 @default.
• W2103138314 hasConceptScore W2103138314C86803240 @default.
• W2103138314 hasConceptScore W2103138314C90132467 @default.
• W2103138314 hasIssue "7" @default.
• W2103138314 hasLocation W21031383141 @default.
• W2103138314 hasLocation W21031383142 @default.
• W2103138314 hasLocation W21031383143 @default.
• W2103138314 hasLocation W21031383144 @default.
• W2103138314 hasOpenAccess W2103138314 @default.
• W2103138314 hasPrimaryLocation W21031383141 @default.
• W2103138314 hasRelatedWork W1596915595 @default.
• W2103138314 hasRelatedWork W1968060200 @default.
• W2103138314 hasRelatedWork W2001531238 @default.

• next