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- W2103140967 abstract "Objectives Pseudotumours (abnormal peri-prosthetic soft-tissue reactions) following metal-on-metal hip resurfacing arthroplasty (MoMHRA) have been associated with elevated metal ion levels, suggesting that excessive wear may occur due to edge-loading of these MoM implants. This study aimed to quantify in vivo edge-loading in MoMHRA patients with and without pseudotumours during functional activities. Methods The duration and magnitude of edge-loading in vivo was quantified during functional activities by combining the dynamic hip joint segment contact force calculated from the three-dimensional (3D) motion analysis system with the 3D reconstruction of orientation of the acetabular component and each patient’s specific hip joint centre, based on CT scans. Results Edge-loading in the hips with pseudotumours occurred with a four-fold increase in duration and magnitude of force compared with the hips without pseudotumours (p = 0.02). Conclusions The study provides the first in vivo evidence to support that edge-loading is an important mechanism that leads to localised excessive wear (edge-wear), with subsequent elevation of metal ion levels in MoMHRA patients with pseudotumours." @default.
- W2103140967 created "2016-06-24" @default.
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- W2103140967 date "2012-04-01" @default.
- W2103140967 modified "2023-09-27" @default.
- W2103140967 title "<i>In vivo</i> evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours" @default.
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- W2103140967 doi "https://doi.org/10.1302/2046-3758.14.2000019" @default.
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