FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103162575> ?p ?o ?g. }

• W2103162575 abstract "Current chemotherapies of cutaneous leihmaniasis have faced to some problems and limitations; Development of new leishmanicidal drugs from different sources like herbal plants, are crucially important. The objective of the present study was evaluation of in vitro activity of Alkanna frigida extracts in comparison with glucantime against Leishmania major.L. major promastigotes were exposed to different concentrations of the A. frigida extracts, processed by ethyl acetate, ethanol, hexane and chloroform. The inhibitory effect, as the IC50, were calculated after 24, 48 and 72 hours by linear regression analysis values of the concentrations employed.The significant inhibition was observed after 24 and 48 hours with different concentrations of compounds (p < 0.05 in all tests). All extracts had potent activity against proliferation of the promastigotes, comparing to the untreated negative control. It could compete with the glucantime efficacy in some concentrations. Ethyl acetate and ethanol extractions showed potent IC50 value, 106 µg/ml and 86 µg/ml, respectively. Hexane and chloroform extractions had poor efficacy after 24 hours; however, the efficacy increased after 48 and 72 hours.The results indicated that the A. frigida has appropriate inhibitory effects on the growth of L. major promastigotes in vitro and can be of herbal targets for further investigation in vivo." @default.
• W2103162575 created "2016-06-24" @default.
• W2103162575 creator A5030500934 @default.
• W2103162575 creator A5035603637 @default.
• W2103162575 creator A5055647542 @default.
• W2103162575 creator A5069983541 @default.
• W2103162575 creator A5082913537 @default.
• W2103162575 date "2013-06-01" @default.
• W2103162575 modified "2023-09-23" @default.
• W2103162575 title "In vitro activity of Alkanna frigida extracts in comparison with glucantime against Leishmania major." @default.
• W2103162575 cites W144060592 @default.
• W2103162575 cites W1558689307 @default.
• W2103162575 cites W1963542761 @default.
• W2103162575 cites W1981968564 @default.
• W2103162575 cites W1986903456 @default.
• W2103162575 cites W1989552486 @default.
• W2103162575 cites W1991873424 @default.
• W2103162575 cites W1995528124 @default.
• W2103162575 cites W2026799139 @default.
• W2103162575 cites W2035231415 @default.
• W2103162575 cites W2040858346 @default.
• W2103162575 cites W2060238076 @default.
• W2103162575 cites W2066954635 @default.
• W2103162575 cites W2068541511 @default.
• W2103162575 cites W2085043016 @default.
• W2103162575 cites W2107915297 @default.
• W2103162575 cites W2116833565 @default.
• W2103162575 cites W2146464411 @default.
• W2103162575 cites W2156820107 @default.
• W2103162575 cites W2246211033 @default.
• W2103162575 cites W2253577618 @default.
• W2103162575 cites W22820660 @default.
• W2103162575 cites W2500912346 @default.
• W2103162575 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3696856" @default.
• W2103162575 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23825738" @default.
• W2103162575 hasPublicationYear "2013" @default.
• W2103162575 type Work @default.
• W2103162575 sameAs 2103162575 @default.
• W2103162575 citedByCount "2" @default.
• W2103162575 countsByYear W21031625752016 @default.
• W2103162575 countsByYear W21031625752017 @default.
• W2103162575 crossrefType "journal-article" @default.
• W2103162575 hasAuthorship W2103162575A5030500934 @default.
• W2103162575 hasAuthorship W2103162575A5035603637 @default.
• W2103162575 hasAuthorship W2103162575A5055647542 @default.
• W2103162575 hasAuthorship W2103162575A5069983541 @default.
• W2103162575 hasAuthorship W2103162575A5082913537 @default.
• W2103162575 hasConcept C136764020 @default.
• W2103162575 hasConcept C150903083 @default.
• W2103162575 hasConcept C185592680 @default.
• W2103162575 hasConcept C202751555 @default.
• W2103162575 hasConcept C207001950 @default.
• W2103162575 hasConcept C2779858419 @default.
• W2103162575 hasConcept C2780161600 @default.
• W2103162575 hasConcept C2780599195 @default.
• W2103162575 hasConcept C2781092759 @default.
• W2103162575 hasConcept C2781144210 @default.
• W2103162575 hasConcept C41008148 @default.
• W2103162575 hasConcept C43617362 @default.
• W2103162575 hasConcept C55493867 @default.
• W2103162575 hasConcept C556039675 @default.
• W2103162575 hasConcept C71924100 @default.
• W2103162575 hasConcept C71928629 @default.
• W2103162575 hasConcept C86803240 @default.
• W2103162575 hasConcept C98274493 @default.
• W2103162575 hasConceptScore W2103162575C136764020 @default.
• W2103162575 hasConceptScore W2103162575C150903083 @default.
• W2103162575 hasConceptScore W2103162575C185592680 @default.
• W2103162575 hasConceptScore W2103162575C202751555 @default.
• W2103162575 hasConceptScore W2103162575C207001950 @default.
• W2103162575 hasConceptScore W2103162575C2779858419 @default.
• W2103162575 hasConceptScore W2103162575C2780161600 @default.
• W2103162575 hasConceptScore W2103162575C2780599195 @default.
• W2103162575 hasConceptScore W2103162575C2781092759 @default.
• W2103162575 hasConceptScore W2103162575C2781144210 @default.
• W2103162575 hasConceptScore W2103162575C41008148 @default.
• W2103162575 hasConceptScore W2103162575C43617362 @default.
• W2103162575 hasConceptScore W2103162575C55493867 @default.
• W2103162575 hasConceptScore W2103162575C556039675 @default.
• W2103162575 hasConceptScore W2103162575C71924100 @default.
• W2103162575 hasConceptScore W2103162575C71928629 @default.
• W2103162575 hasConceptScore W2103162575C86803240 @default.
• W2103162575 hasConceptScore W2103162575C98274493 @default.
• W2103162575 hasLocation W21031625751 @default.
• W2103162575 hasOpenAccess W2103162575 @default.
• W2103162575 hasPrimaryLocation W21031625751 @default.
• W2103162575 hasRelatedWork W1481961580 @default.
• W2103162575 hasRelatedWork W1964706364 @default.
• W2103162575 hasRelatedWork W1989585750 @default.
• W2103162575 hasRelatedWork W2100196421 @default.
• W2103162575 hasRelatedWork W2113209548 @default.
• W2103162575 hasRelatedWork W2118592167 @default.
• W2103162575 hasRelatedWork W2163663729 @default.
• W2103162575 hasRelatedWork W2164456254 @default.
• W2103162575 hasRelatedWork W2409368100 @default.
• W2103162575 hasRelatedWork W2584811688 @default.
• W2103162575 hasRelatedWork W2641369061 @default.
• W2103162575 hasRelatedWork W2888628267 @default.
• W2103162575 hasRelatedWork W2892674849 @default.
• W2103162575 hasRelatedWork W2898047763 @default.

• next