FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103167528> ?p ?o ?g. }

• W2103167528 endingPage "159" @default.
• W2103167528 startingPage "145" @default.
• W2103167528 abstract "The last decade has seen a transformation in understanding of the role of membrane-bound interfacial water. Whereas until recently water was treated principally as a continuum (primarily screening charges of lipids and proteins), it has become apparent recently that consideration of water's molecular-level properties is critical in understanding a variety of biochemical and biophysical processes. Here we investigate the structure and dynamics of water in contact with a monolayer of artificial lung surfactant, composed of four types of lipids and one protein. We probe this water using frequency-domain sum-frequency generation (SFG) spectroscopy, and a newly developed time-domain, three-pulse technique, in which the vibrational relaxation of interfacial water molecules is followed in real time. We characterize interfacial water in three systems: a monolayer of the pure lipid that is the majority of the lung surfactant mixture, a monolayer of the four lipids constituting the mixture, and a monolayer of the four lipids and the protein. We find subtle differences in the water structure and dynamics that depend on the mixture density and composition. In particular, frequency-domain measurements suggest that in the lipid mixture and the lipid mixture + protein, the relatively bulky lipids (those that have either three or unsaturated hydrocarbon tails) tend to be squeezed out at higher pressure. Measurements using the time-domain, three-pulse technique make clear that structural relaxation of interfacial water is significantly slowed down upon adding small amounts of protein to the lipids. Both results are consistent with prior measurements using other techniques in which more fluid lipids were shown to be 'squeezed out' of lung surfactant at high compression and the role of protein in the mixture was demonstrated to be a catalyst for the formation of multilayers under compression that are subsequently reintegrated into the monolayer on expansion." @default.
• W2103167528 created "2016-06-24" @default.
• W2103167528 creator A5017647814 @default.
• W2103167528 creator A5026050967 @default.
• W2103167528 creator A5048925903 @default.
• W2103167528 creator A5050036297 @default.
• W2103167528 date "2009-01-01" @default.
• W2103167528 modified "2023-09-25" @default.
• W2103167528 title "Structure and dynamics of interfacial water in model lung surfactants" @default.
• W2103167528 cites W1563494356 @default.
• W2103167528 cites W1966176489 @default.
• W2103167528 cites W1968585069 @default.
• W2103167528 cites W1971211600 @default.
• W2103167528 cites W1973506949 @default.
• W2103167528 cites W1977088104 @default.
• W2103167528 cites W1977433201 @default.
• W2103167528 cites W1979317008 @default.
• W2103167528 cites W1981764974 @default.
• W2103167528 cites W1982385940 @default.
• W2103167528 cites W1983518360 @default.
• W2103167528 cites W1985839449 @default.
• W2103167528 cites W1996300479 @default.
• W2103167528 cites W1998609376 @default.
• W2103167528 cites W2000827899 @default.
• W2103167528 cites W2001689805 @default.
• W2103167528 cites W2004715309 @default.
• W2103167528 cites W2006043456 @default.
• W2103167528 cites W2007603804 @default.
• W2103167528 cites W2008460998 @default.
• W2103167528 cites W2010697548 @default.
• W2103167528 cites W2012989473 @default.
• W2103167528 cites W2014903703 @default.
• W2103167528 cites W2021566521 @default.
• W2103167528 cites W2026218538 @default.
• W2103167528 cites W2028250245 @default.
• W2103167528 cites W2029246506 @default.
• W2103167528 cites W2029550043 @default.
• W2103167528 cites W2032910673 @default.
• W2103167528 cites W2039820957 @default.
• W2103167528 cites W2041132322 @default.
• W2103167528 cites W2042611887 @default.
• W2103167528 cites W2045111209 @default.
• W2103167528 cites W2047810273 @default.
• W2103167528 cites W2051698784 @default.
• W2103167528 cites W2051939592 @default.
• W2103167528 cites W2056848570 @default.
• W2103167528 cites W2059314942 @default.
• W2103167528 cites W2062234578 @default.
• W2103167528 cites W2063995227 @default.
• W2103167528 cites W2065335146 @default.
• W2103167528 cites W2065994791 @default.
• W2103167528 cites W2072592896 @default.
• W2103167528 cites W2074623909 @default.
• W2103167528 cites W2075956033 @default.
• W2103167528 cites W2082204764 @default.
• W2103167528 cites W2082734176 @default.
• W2103167528 cites W2087322664 @default.
• W2103167528 cites W2090619702 @default.
• W2103167528 cites W2104696629 @default.
• W2103167528 cites W2118753407 @default.
• W2103167528 cites W2121517777 @default.
• W2103167528 cites W2125597853 @default.
• W2103167528 cites W2140506809 @default.
• W2103167528 cites W2144385592 @default.
• W2103167528 cites W2144576353 @default.
• W2103167528 cites W2145146108 @default.
• W2103167528 cites W2147304506 @default.
• W2103167528 cites W2150470117 @default.
• W2103167528 cites W2150603940 @default.
• W2103167528 cites W2154389667 @default.
• W2103167528 cites W2161348276 @default.
• W2103167528 cites W4236168401 @default.
• W2103167528 cites W4245635761 @default.
• W2103167528 doi "https://doi.org/10.1039/b805858j" @default.
• W2103167528 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19227356" @default.
• W2103167528 hasPublicationYear "2009" @default.
• W2103167528 type Work @default.
• W2103167528 sameAs 2103167528 @default.
• W2103167528 citedByCount "17" @default.
• W2103167528 countsByYear W21031675282012 @default.
• W2103167528 countsByYear W21031675282013 @default.
• W2103167528 countsByYear W21031675282014 @default.
• W2103167528 countsByYear W21031675282015 @default.
• W2103167528 countsByYear W21031675282016 @default.
• W2103167528 countsByYear W21031675282018 @default.
• W2103167528 crossrefType "journal-article" @default.
• W2103167528 hasAuthorship W2103167528A5017647814 @default.
• W2103167528 hasAuthorship W2103167528A5026050967 @default.
• W2103167528 hasAuthorship W2103167528A5048925903 @default.
• W2103167528 hasAuthorship W2103167528A5050036297 @default.
• W2103167528 hasConcept C113196181 @default.
• W2103167528 hasConcept C12554922 @default.
• W2103167528 hasConcept C127413603 @default.
• W2103167528 hasConcept C147597530 @default.
• W2103167528 hasConcept C15744967 @default.
• W2103167528 hasConcept C159467904 @default.
• W2103167528 hasConcept C178790620 @default.
• W2103167528 hasConcept C185592680 @default.

• next