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• W2103167898 abstract "SUMMARY Initial experiments demonstrated that the plasmid R6K cannot be transferred to or maintained readily in the E. coli DNA polymerase I deficient strain JG138 polA1 . Results with E. coli MM386 polA12 (R6K), which has a temperature sensitive polymerase I enzyme, showed cell division becomes abnormal when the polymerase I enzyme of the host bacteria is inactivated at the restrictive temperature. Under conditions of polymerase I deficiency, R6K replication, as measured by monitoring R-factor-mediated β-lactamase activity, also becomes abnormal with the loss of multiple R6K copies per cell and the apparent maintenance of a single R-factor copy per cell." @default.
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• W2103167898 date "1978-08-01" @default.
• W2103167898 modified "2023-09-27" @default.
• W2103167898 title "Interaction between the plasmid R6K andEscherichia coliwith defective DNA polymerase I" @default.
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• W2103167898 doi "https://doi.org/10.1017/s0016672300018498" @default.
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