FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103174375> ?p ?o ?g. }

• W2103174375 endingPage "103" @default.
• W2103174375 startingPage "88" @default.
• W2103174375 abstract "The hydration of CO(2) and the dehydration of HCO(3)(-) catalyzed by the carbonic anhydrases is accompanied by the transfer of protons between solution and the zinc-bound water molecule in the active site. This transfer is facilitated by amino acid residues of the enzyme which act as intramolecular proton shuttles; variants of carbonic anhydrase lacking such shuttle residues are enhanced or rescued in catalysis by intermolecular proton transfer from donors such as imidazole in solution. The resulting rate constants for proton transfer when compared with the values of the pK(a) of the donor and acceptor give Bronsted plots of high curvature. These data are described by Marcus theory which shows an intrinsic barrier for proton transfer from 1 to 2 kcal/mol and work terms or thermodynamic contributions to the free energy of reaction from 4 to10 kcal/mol. The interpretation of these Marcus parameters is discussed in terms of the well-studied pathway of the catalysis and structure of the enzymes." @default.
• W2103174375 created "2016-06-24" @default.
• W2103174375 creator A5034873616 @default.
• W2103174375 date "2000-05-01" @default.
• W2103174375 modified "2023-09-30" @default.
• W2103174375 title "Marcus rate theory applied to enzymatic proton transfer" @default.
• W2103174375 cites W138562473 @default.
• W2103174375 cites W1497413258 @default.
• W2103174375 cites W1498408076 @default.
• W2103174375 cites W1573899446 @default.
• W2103174375 cites W1585542991 @default.
• W2103174375 cites W1604147974 @default.
• W2103174375 cites W1651579 @default.
• W2103174375 cites W1965969235 @default.
• W2103174375 cites W1966139210 @default.
• W2103174375 cites W1967449452 @default.
• W2103174375 cites W1971499243 @default.
• W2103174375 cites W1973040844 @default.
• W2103174375 cites W1973565199 @default.
• W2103174375 cites W1974404541 @default.
• W2103174375 cites W1974988689 @default.
• W2103174375 cites W1977150033 @default.
• W2103174375 cites W1978449065 @default.
• W2103174375 cites W1983563055 @default.
• W2103174375 cites W1988295340 @default.
• W2103174375 cites W1989384815 @default.
• W2103174375 cites W1991072674 @default.
• W2103174375 cites W1991524595 @default.
• W2103174375 cites W1998931710 @default.
• W2103174375 cites W1999437614 @default.
• W2103174375 cites W2001270915 @default.
• W2103174375 cites W2006241070 @default.
• W2103174375 cites W2006569122 @default.
• W2103174375 cites W2009217088 @default.
• W2103174375 cites W2011571293 @default.
• W2103174375 cites W2013048913 @default.
• W2103174375 cites W2016065841 @default.
• W2103174375 cites W2019175962 @default.
• W2103174375 cites W2023649594 @default.
• W2103174375 cites W2033850470 @default.
• W2103174375 cites W2034972604 @default.
• W2103174375 cites W2035046825 @default.
• W2103174375 cites W2036005020 @default.
• W2103174375 cites W2038501644 @default.
• W2103174375 cites W2040935686 @default.
• W2103174375 cites W2042172714 @default.
• W2103174375 cites W2044634803 @default.
• W2103174375 cites W2045120197 @default.
• W2103174375 cites W2046801125 @default.
• W2103174375 cites W2047817340 @default.
• W2103174375 cites W2048016835 @default.
• W2103174375 cites W2050516083 @default.
• W2103174375 cites W2060102273 @default.
• W2103174375 cites W2062195240 @default.
• W2103174375 cites W2063800570 @default.
• W2103174375 cites W2064762282 @default.
• W2103174375 cites W2065447578 @default.
• W2103174375 cites W2065934234 @default.
• W2103174375 cites W2069339217 @default.
• W2103174375 cites W2071155271 @default.
• W2103174375 cites W2073124751 @default.
• W2103174375 cites W2077191757 @default.
• W2103174375 cites W2077254715 @default.
• W2103174375 cites W2077865653 @default.
• W2103174375 cites W2078184681 @default.
• W2103174375 cites W2083361076 @default.
• W2103174375 cites W2085323932 @default.
• W2103174375 cites W2085517713 @default.
• W2103174375 cites W2087227246 @default.
• W2103174375 cites W2091237955 @default.
• W2103174375 cites W2091454160 @default.
• W2103174375 cites W2111008899 @default.
• W2103174375 cites W2118262335 @default.
• W2103174375 cites W2120203962 @default.
• W2103174375 cites W2126085054 @default.
• W2103174375 cites W2126734375 @default.
• W2103174375 cites W2127400370 @default.
• W2103174375 cites W2138360835 @default.
• W2103174375 cites W2141029077 @default.
• W2103174375 cites W2153023761 @default.
• W2103174375 cites W2314342777 @default.
• W2103174375 cites W2611493662 @default.
• W2103174375 cites W2951322477 @default.
• W2103174375 cites W3004481420 @default.
• W2103174375 cites W315405827 @default.
• W2103174375 cites W36235469 @default.
• W2103174375 cites W4210858769 @default.
• W2103174375 cites W4234949855 @default.
• W2103174375 cites W969103351 @default.
• W2103174375 doi "https://doi.org/10.1016/s0005-2728(00)00061-x" @default.
• W2103174375 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10812026" @default.
• W2103174375 hasPublicationYear "2000" @default.
• W2103174375 type Work @default.
• W2103174375 sameAs 2103174375 @default.
• W2103174375 citedByCount "88" @default.
• W2103174375 countsByYear W21031743752012 @default.
• W2103174375 countsByYear W21031743752013 @default.
• W2103174375 countsByYear W21031743752014 @default.

• next