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- W2103177513 abstract "Extensive peritumoral neoplastic lymphovascular invasion (ePVI) is a marker of aggressiveness in invasive breast carcinoma (BC).We explored the impact of ePVI on different BC subtypes. In a total of 2,116 BCs, 91 ePVI-BCs, 70 inflammatory breast carcinomas (IBCs), and 114 casual BCs as a control group (CG-BC) were recruited.Patients affected by ePVI-BC were younger, had larger tumors, higher histologic grade, elevated Ki-67 score, Her2/neu overexpressed, and more lymph node metastases compared with CG-BC (P < .001). Interestingly, only younger mean age at diagnosis differentiated patients with ePVI-BC from patients affected by IBC. ePVI-BC showed a clinical outcome intermediate between the prognoses of IBC and CG-BC.Results suggest that ePVI-BC and IBC may share some pathologic processes, providing a novel perspective on the heterogeneity of BC. Epidemiologic data and molecular studies on gene expression features are needed to rationally classify these tumors into their identified subtypes." @default.
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- W2103177513 date "2014-09-01" @default.
- W2103177513 modified "2023-10-01" @default.
- W2103177513 title "Comparison Between Invasive Breast Cancer With Extensive Peritumoral Vascular Invasion and Inflammatory Breast Carcinoma" @default.
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- W2103177513 doi "https://doi.org/10.1309/ajcpoxkx67kraovm" @default.
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