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- W2103189978 endingPage "1270" @default.
- W2103189978 startingPage "1260" @default.
- W2103189978 abstract "Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer death in the Western world. Owing to a lack of specific symptoms and no accessible precursor lesions, primary diagnosis is commonly delayed, resulting in only 15%-20% of patients with potentially curable disease. The standard of care in advanced pancreatic cancer has improved. Apart from gemcitabine (plus erlotinib), FOLFIRINOX and the combination of gemcitabine plus nab-paclitaxel are novel and promising therapeutic options for patients with metastatic PDAC. A better molecular understanding of pancreatic cancer has led to the identification of a variety of potential molecular therapeutic targets. Many targeted therapies are currently under clinical evaluation in combination with standard therapies for PDAC. This review highlights the current status of targeted therapies and their potential benefit for the treatment of advanced PDAC." @default.
- W2103189978 created "2016-06-24" @default.
- W2103189978 creator A5021152840 @default.
- W2103189978 creator A5034891779 @default.
- W2103189978 creator A5055082801 @default.
- W2103189978 date "2014-07-01" @default.
- W2103189978 modified "2023-09-24" @default.
- W2103189978 title "Smarter drugs emerging in pancreatic cancer therapy" @default.
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