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- W2103202904 abstract "Review question/ objective The aim of this review is to compare the efficacy of repetitive transcranial-magnetic stimulation (rTMS) with electroconvulsive therapy (ECT) in the treatment of medication resistant major depressive disorder. Inclusion Criteria Types of participants This review will consider all randomized controlled trials that attempt to compare the efficacy of rTMS versus ECT in the treatment of medication resistant major depressive disorder; given for patients of any age and gender with a diagnosis of major depression disorder, with or without psychotic features according to either the DSM–IV (American Psychiatric Association, 1994) or ICD–10 (World Health Organization, 1993) diagnostic criteria. All patients included in this study have to have been judged as clinically appropriate for a course of ECT or rTMS based on the chronicity and severity of depression, presence of multiple medication trials and/or lack of adequate response or intolerance to pharmacotherapy. Types of intervention(s) This particular review will include all randomized controlled trial studies that compared the efficacy of rTMS with ECT therapy in the treatment of medication resistant major depressive disorder, given for patients of any age and gender. Types of outcomes The primary outcome measure of this review will be the score on the Hamilton Depression Rating Scale (HAM-D) and the proportion of patients with remissions (Hamilton score, < 8) after treatment with rTMS or ECT. Secondary outcomes will include mood self-ratings on the Beck Depression Inventory-II and Visual Analogue Mood Scales, Brief Psychiatric Rating Scale (BPRS) score, Young Mania Rating Scale (YMS), Clinical Global Impression scale (CGI) and both self-reported and observer-rated cognitive changes." @default.
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- W2103202904 date "2013-11-01" @default.
- W2103202904 modified "2023-09-27" @default.
- W2103202904 title "Efficacy of repetitive transcranial magnetic stimulation versus electroconvulsive therapy in the treatment of medication resistant major depressive disorder: a systematic review protocol" @default.
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- W2103202904 doi "https://doi.org/10.11124/jbisrir-2013-897" @default.
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