Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103213616> ?p ?o ?g. }
- W2103213616 endingPage "904" @default.
- W2103213616 startingPage "897" @default.
- W2103213616 abstract "Purpose: To determine the diagnostic performance of minimally invasive autopsy (MIA) for detection of causes of death and to investigate the feasibility of MIA as an alternative to conventional autopsy (CA) in the clinical setting. Materials and Methods: The institutional review board approved the MIA procedure and study, and informed consent was obtained for all deceased patients from relatives. Thirty deceased patients (19 men, 11 women; age range, 46–79 years), for whom family permission for CA on medical grounds had already been obtained, underwent additional evaluation with MIA prior to CA. MIA consisted of whole-body 16-section computed tomography (CT) and 1.5-T magnetic resonance (MR) imaging, followed by ultrasonography-guided 12-guage needle biopsy of heart, both lungs, liver, both kidneys, and spleen. Percentage agreement between MIA and CA on cause of death was evaluated. Sensitivity and corresponding 95% confidence intervals (CIs) of MIA for detection of overall (major plus minor) findings, with CA as the reference standard, were calculated. Specificity was calculated for overall findings. Sensitivity analysis was performed to explore the effect of the clustered nature of the data. Results: In 23 patients (77%), MIA and CA were in agreement on the cause of death. Sensitivity of MIA for detection of overall findings and detection of major findings was 93% (95% CI: 90%, 96%) and 94% (95% CI: 87%, 97%), respectively. Specificity was 99% (95% CI: 98%, 99%) for detection of overall findings. MIA failed to demonstrate acute myocardial infarction as the cause of death in four patients. Sensitivity analysis indicated a negligible correlation between observations within each patient. CT was superior to MR for detection of pneumothorax and calcifications. MR was superior to CT for detection of brain abnormalities and pulmonary embolus. With biopsy only, detection of disease in 55 organs was possible, which included 27 major findings. Conclusion: MIA is a feasible procedure with high diagnostic performance for detection of common causes of death such as pneumonia and sepsis; MIA failed to demonstrate cardiac diseases, such as acute myocardial infarction and endocarditis, as underlying cause of death. Supplemental material: http://radiology.rsnajnls.org/cgi/content/full/250/3/897//DC1 © RSNA, 2009" @default.
- W2103213616 created "2016-06-24" @default.
- W2103213616 creator A5011584764 @default.
- W2103213616 creator A5014404163 @default.
- W2103213616 creator A5026752223 @default.
- W2103213616 creator A5039934713 @default.
- W2103213616 creator A5047573361 @default.
- W2103213616 creator A5087945700 @default.
- W2103213616 date "2009-03-01" @default.
- W2103213616 modified "2023-10-16" @default.
- W2103213616 title "Minimally Invasive Autopsy: An Alternative to Conventional Autopsy?" @default.
- W2103213616 cites W1490823646 @default.
- W2103213616 cites W1555138916 @default.
- W2103213616 cites W1934757742 @default.
- W2103213616 cites W1976724752 @default.
- W2103213616 cites W1985122803 @default.
- W2103213616 cites W1999244727 @default.
- W2103213616 cites W2006447100 @default.
- W2103213616 cites W2007556114 @default.
- W2103213616 cites W2009576786 @default.
- W2103213616 cites W2021409788 @default.
- W2103213616 cites W2033752366 @default.
- W2103213616 cites W2071007244 @default.
- W2103213616 cites W2075633000 @default.
- W2103213616 cites W2076640801 @default.
- W2103213616 cites W2080147859 @default.
- W2103213616 cites W2093087577 @default.
- W2103213616 cites W2099177786 @default.
- W2103213616 cites W2113997682 @default.
- W2103213616 cites W2132037185 @default.
- W2103213616 cites W2135347027 @default.
- W2103213616 cites W2150290224 @default.
- W2103213616 cites W2161537555 @default.
- W2103213616 cites W2321965186 @default.
- W2103213616 cites W4232875550 @default.
- W2103213616 doi "https://doi.org/10.1148/radiol.2503080421" @default.
- W2103213616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19244053" @default.
- W2103213616 hasPublicationYear "2009" @default.
- W2103213616 type Work @default.
- W2103213616 sameAs 2103213616 @default.
- W2103213616 citedByCount "171" @default.
- W2103213616 countsByYear W21032136162012 @default.
- W2103213616 countsByYear W21032136162013 @default.
- W2103213616 countsByYear W21032136162014 @default.
- W2103213616 countsByYear W21032136162015 @default.
- W2103213616 countsByYear W21032136162016 @default.
- W2103213616 countsByYear W21032136162017 @default.
- W2103213616 countsByYear W21032136162018 @default.
- W2103213616 countsByYear W21032136162019 @default.
- W2103213616 countsByYear W21032136162020 @default.
- W2103213616 countsByYear W21032136162021 @default.
- W2103213616 countsByYear W21032136162022 @default.
- W2103213616 countsByYear W21032136162023 @default.
- W2103213616 crossrefType "journal-article" @default.
- W2103213616 hasAuthorship W2103213616A5011584764 @default.
- W2103213616 hasAuthorship W2103213616A5014404163 @default.
- W2103213616 hasAuthorship W2103213616A5026752223 @default.
- W2103213616 hasAuthorship W2103213616A5039934713 @default.
- W2103213616 hasAuthorship W2103213616A5047573361 @default.
- W2103213616 hasAuthorship W2103213616A5087945700 @default.
- W2103213616 hasConcept C126322002 @default.
- W2103213616 hasConcept C126838900 @default.
- W2103213616 hasConcept C141071460 @default.
- W2103213616 hasConcept C143409427 @default.
- W2103213616 hasConcept C2779134260 @default.
- W2103213616 hasConcept C2779504383 @default.
- W2103213616 hasConcept C29374701 @default.
- W2103213616 hasConcept C2989005 @default.
- W2103213616 hasConcept C44249647 @default.
- W2103213616 hasConcept C71924100 @default.
- W2103213616 hasConceptScore W2103213616C126322002 @default.
- W2103213616 hasConceptScore W2103213616C126838900 @default.
- W2103213616 hasConceptScore W2103213616C141071460 @default.
- W2103213616 hasConceptScore W2103213616C143409427 @default.
- W2103213616 hasConceptScore W2103213616C2779134260 @default.
- W2103213616 hasConceptScore W2103213616C2779504383 @default.
- W2103213616 hasConceptScore W2103213616C29374701 @default.
- W2103213616 hasConceptScore W2103213616C2989005 @default.
- W2103213616 hasConceptScore W2103213616C44249647 @default.
- W2103213616 hasConceptScore W2103213616C71924100 @default.
- W2103213616 hasIssue "3" @default.
- W2103213616 hasLocation W21032136161 @default.
- W2103213616 hasLocation W21032136162 @default.
- W2103213616 hasOpenAccess W2103213616 @default.
- W2103213616 hasPrimaryLocation W21032136161 @default.
- W2103213616 hasRelatedWork W1586374228 @default.
- W2103213616 hasRelatedWork W2002120878 @default.
- W2103213616 hasRelatedWork W2003938723 @default.
- W2103213616 hasRelatedWork W2047967234 @default.
- W2103213616 hasRelatedWork W2118496982 @default.
- W2103213616 hasRelatedWork W2364998975 @default.
- W2103213616 hasRelatedWork W2369162477 @default.
- W2103213616 hasRelatedWork W2439875401 @default.
- W2103213616 hasRelatedWork W4238867864 @default.
- W2103213616 hasRelatedWork W2525756941 @default.
- W2103213616 hasVolume "250" @default.
- W2103213616 isParatext "false" @default.
- W2103213616 isRetracted "false" @default.