FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103226304> ?p ?o ?g. }

• W2103226304 endingPage "81" @default.
• W2103226304 startingPage "2374" @default.
• W2103226304 abstract "To analyze the performance of different commercial enzyme immunoassay (EIA) kits for measuring antinuclear antibodies (ANA) specific for dsDNA, SSB/La, Sm, and Scl-70.EIA kits for detection of ANA from 9 commercial manufacturers were evaluated. The manufacturers were advised that they would be sent coded sera containing mixtures of the Arthritis Foundation/Centers for Disease Control reference reagents, and that they were to use their own test kits to analyze the antibody specificities of these sera and to report the data, in optical density (OD) units or their equivalent. Independently, 12 investigators in academic institutions who have done research in this field agreed to participate in a parallel study. The concentration of the antibodies and the specificities were blinded to the analysts and the coefficients of variation (CV) were computed for each participant.There were statistically significant differences between laboratories in terms of CV for all 9 kits tested. With the exception of one kit, there were no significant CV differences between the various autoantibody kits provided by each manufacturer and, with the exception of kits from 2 manufacturers, there were no significant differences between the various antibody kits in terms of reproducibility (CV). From the point of view of interlaboratory variability, manufacturers could be separated into either a high or low performance group.We found a disconcertingly large range of performance characteristics in the various laboratories, which could be quite detrimental in routine utilization of EIA ANA kits. Clinicians should be aware of the performance issues raised in our study, and should know and be involved in how their service laboratory assesses its own performance and the performance of commercial testing systems utilized. Manufacturers and clinical laboratories need to exercise constant quality assurance and surveillance of kit performance in the hands of medical laboratory technologists involved in routine testing." @default.
• W2103226304 created "2016-06-24" @default.
• W2103226304 creator A5011458972 @default.
• W2103226304 creator A5020989900 @default.
• W2103226304 creator A5024608868 @default.
• W2103226304 creator A5029479045 @default.
• W2103226304 creator A5034462401 @default.
• W2103226304 creator A5045265035 @default.
• W2103226304 creator A5053140449 @default.
• W2103226304 creator A5056289423 @default.
• W2103226304 creator A5063329660 @default.
• W2103226304 creator A5065446697 @default.
• W2103226304 creator A5066602987 @default.
• W2103226304 creator A5066746944 @default.
• W2103226304 creator A5069522474 @default.
• W2103226304 creator A5070386251 @default.
• W2103226304 creator A5076647363 @default.
• W2103226304 creator A5086838203 @default.
• W2103226304 creator A5087744761 @default.
• W2103226304 creator A5090028133 @default.
• W2103226304 date "2003-11-01" @default.
• W2103226304 modified "2023-09-25" @default.
• W2103226304 title "A critical evaluation of enzyme immunoassay kits for detection of antinuclear autoantibodies of defined specificities. III. Comparative performance characteristics of academic and manufacturers' laboratories." @default.
• W2103226304 cites W1978517527 @default.
• W2103226304 cites W1999158929 @default.
• W2103226304 cites W2000332930 @default.
• W2103226304 cites W2000612383 @default.
• W2103226304 cites W2030223911 @default.
• W2103226304 cites W2044196548 @default.
• W2103226304 cites W2082796552 @default.
• W2103226304 cites W2095178856 @default.
• W2103226304 cites W2097419280 @default.
• W2103226304 cites W21981744 @default.
• W2103226304 cites W2325525533 @default.
• W2103226304 cites W2401307393 @default.
• W2103226304 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14677180" @default.
• W2103226304 hasPublicationYear "2003" @default.
• W2103226304 type Work @default.
• W2103226304 sameAs 2103226304 @default.
• W2103226304 citedByCount "16" @default.
• W2103226304 countsByYear W21032263042012 @default.
• W2103226304 countsByYear W21032263042013 @default.
• W2103226304 countsByYear W21032263042014 @default.
• W2103226304 countsByYear W21032263042016 @default.
• W2103226304 countsByYear W21032263042017 @default.
• W2103226304 countsByYear W21032263042018 @default.
• W2103226304 crossrefType "journal-article" @default.
• W2103226304 hasAuthorship W2103226304A5011458972 @default.
• W2103226304 hasAuthorship W2103226304A5020989900 @default.
• W2103226304 hasAuthorship W2103226304A5024608868 @default.
• W2103226304 hasAuthorship W2103226304A5029479045 @default.
• W2103226304 hasAuthorship W2103226304A5034462401 @default.
• W2103226304 hasAuthorship W2103226304A5045265035 @default.
• W2103226304 hasAuthorship W2103226304A5053140449 @default.
• W2103226304 hasAuthorship W2103226304A5056289423 @default.
• W2103226304 hasAuthorship W2103226304A5063329660 @default.
• W2103226304 hasAuthorship W2103226304A5065446697 @default.
• W2103226304 hasAuthorship W2103226304A5066602987 @default.
• W2103226304 hasAuthorship W2103226304A5066746944 @default.
• W2103226304 hasAuthorship W2103226304A5069522474 @default.
• W2103226304 hasAuthorship W2103226304A5070386251 @default.
• W2103226304 hasAuthorship W2103226304A5076647363 @default.
• W2103226304 hasAuthorship W2103226304A5086838203 @default.
• W2103226304 hasAuthorship W2103226304A5087744761 @default.
• W2103226304 hasAuthorship W2103226304A5090028133 @default.
• W2103226304 hasConcept C149443304 @default.
• W2103226304 hasConcept C159654299 @default.
• W2103226304 hasConcept C163764329 @default.
• W2103226304 hasConcept C185592680 @default.
• W2103226304 hasConcept C203014093 @default.
• W2103226304 hasConcept C2780420688 @default.
• W2103226304 hasConcept C43617362 @default.
• W2103226304 hasConcept C71924100 @default.
• W2103226304 hasConcept C9893847 @default.
• W2103226304 hasConceptScore W2103226304C149443304 @default.
• W2103226304 hasConceptScore W2103226304C159654299 @default.
• W2103226304 hasConceptScore W2103226304C163764329 @default.
• W2103226304 hasConceptScore W2103226304C185592680 @default.
• W2103226304 hasConceptScore W2103226304C203014093 @default.
• W2103226304 hasConceptScore W2103226304C2780420688 @default.
• W2103226304 hasConceptScore W2103226304C43617362 @default.
• W2103226304 hasConceptScore W2103226304C71924100 @default.
• W2103226304 hasConceptScore W2103226304C9893847 @default.
• W2103226304 hasIssue "11" @default.
• W2103226304 hasLocation W21032263041 @default.
• W2103226304 hasOpenAccess W2103226304 @default.
• W2103226304 hasPrimaryLocation W21032263041 @default.
• W2103226304 hasRelatedWork W1811963047 @default.
• W2103226304 hasRelatedWork W1998508932 @default.
• W2103226304 hasRelatedWork W2016413453 @default.
• W2103226304 hasRelatedWork W2064872372 @default.
• W2103226304 hasRelatedWork W2076041280 @default.
• W2103226304 hasRelatedWork W2103226304 @default.
• W2103226304 hasRelatedWork W2332116053 @default.
• W2103226304 hasRelatedWork W2369071334 @default.
• W2103226304 hasRelatedWork W2411117286 @default.
• W2103226304 hasRelatedWork W4212782300 @default.
• W2103226304 hasVolume "30" @default.

• next