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- W2103252368 abstract "Direct enantioselective reduction of 2´-, 3´- and 4´ -hydroxyacetophenone without protection of the hydroxy moiety was carried out in the presence of (R)- and (S)-alcohol dehydrogenases as biocatalysts. Whereas reduction of 2´-hydroxyacetophenone gave only low to medium conversions, reduction of 3´- and 4´ -hydroxyacetophenone proceeded efficiently leading to the resulting 1-(3- hydroxyphenyl)ethan-1-ol and 1-(4-hydroxyphenyl)ethan-1-ol with high conversion (up to > 95 %) and excellent enantioselectivity (up to > 99% ee)." @default.
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- W2103252368 date "2010-03-01" @default.
- W2103252368 modified "2023-10-14" @default.
- W2103252368 title "Enantioselective Biocatalytic Reduction of Non-protected Hydroxyacetophenones" @default.
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- W2103252368 doi "https://doi.org/10.1515/znb-2010-0317" @default.
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