Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103252468> ?p ?o ?g. }
- W2103252468 endingPage "iv21" @default.
- W2103252468 startingPage "iv17" @default.
- W2103252468 abstract "Vitamin D has been recently associated with several renal, cardiovascular and inflammatory diseases, beyond mineral metabolism and bone health. This is due in part to widespread expression of vitamin D receptor (VDR) on tissues and cells such as heart, kidney, immune cells, brain and muscle. In chronic kidney disease (CKD) and other chronic disorders, vitamin D deficiency [serum 25(OH)D <20 ng/mL] is very common and is associated with adverse outcomes. Paricalcitol, a selective activator of VDR, has demonstrated in several experimental and clinical studies of diabetic and non-diabetic CKD a favourable profile compared to other VDR activators, alone or as add-on to standard therapy. These beneficial effects are mediated by different actions such as reduction of oxidative stress, inflammation, downregulation of cardiac and renal renin expression, downregulation of calcifying genes and direct vascular protective effects. Furthermore, paricalcitol beneficial effects may be independent of baseline serum parathyroid hormone (PTH), calcium and phosphate levels. These benefits should be confirmed in large and well-designed ongoing clinical trials." @default.
- W2103252468 created "2016-06-24" @default.
- W2103252468 creator A5005804630 @default.
- W2103252468 creator A5018160190 @default.
- W2103252468 creator A5052017202 @default.
- W2103252468 creator A5063245254 @default.
- W2103252468 creator A5066461251 @default.
- W2103252468 creator A5079455479 @default.
- W2103252468 date "2012-12-01" @default.
- W2103252468 modified "2023-10-17" @default.
- W2103252468 title "Vitamin D receptor activation and cardiovascular disease" @default.
- W2103252468 cites W1970223241 @default.
- W2103252468 cites W1983032812 @default.
- W2103252468 cites W1985464840 @default.
- W2103252468 cites W1986415554 @default.
- W2103252468 cites W1999841727 @default.
- W2103252468 cites W2015462810 @default.
- W2103252468 cites W2017041470 @default.
- W2103252468 cites W2023213178 @default.
- W2103252468 cites W2023320327 @default.
- W2103252468 cites W2033758176 @default.
- W2103252468 cites W2035221187 @default.
- W2103252468 cites W2041994587 @default.
- W2103252468 cites W2043058954 @default.
- W2103252468 cites W2045514074 @default.
- W2103252468 cites W2053604381 @default.
- W2103252468 cites W2069892521 @default.
- W2103252468 cites W2073168952 @default.
- W2103252468 cites W2078808411 @default.
- W2103252468 cites W2079038330 @default.
- W2103252468 cites W2079719406 @default.
- W2103252468 cites W2079789436 @default.
- W2103252468 cites W2080387599 @default.
- W2103252468 cites W2086905000 @default.
- W2103252468 cites W2089831413 @default.
- W2103252468 cites W2090089306 @default.
- W2103252468 cites W2091670720 @default.
- W2103252468 cites W2103326270 @default.
- W2103252468 cites W2105417592 @default.
- W2103252468 cites W2111387420 @default.
- W2103252468 cites W2113356410 @default.
- W2103252468 cites W2113593985 @default.
- W2103252468 cites W2113748378 @default.
- W2103252468 cites W2114902110 @default.
- W2103252468 cites W2123338619 @default.
- W2103252468 cites W2129096360 @default.
- W2103252468 cites W2132644547 @default.
- W2103252468 cites W2137743950 @default.
- W2103252468 cites W2138506456 @default.
- W2103252468 cites W2142338958 @default.
- W2103252468 cites W2142591987 @default.
- W2103252468 cites W2144431513 @default.
- W2103252468 cites W2148398366 @default.
- W2103252468 cites W2151434420 @default.
- W2103252468 cites W2152573947 @default.
- W2103252468 cites W2159126630 @default.
- W2103252468 cites W2160985613 @default.
- W2103252468 cites W2168828068 @default.
- W2103252468 cites W2727742003 @default.
- W2103252468 cites W3140065338 @default.
- W2103252468 cites W4243235497 @default.
- W2103252468 doi "https://doi.org/10.1093/ndt/gfs534" @default.
- W2103252468 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23258805" @default.
- W2103252468 hasPublicationYear "2012" @default.
- W2103252468 type Work @default.
- W2103252468 sameAs 2103252468 @default.
- W2103252468 citedByCount "52" @default.
- W2103252468 countsByYear W21032524682013 @default.
- W2103252468 countsByYear W21032524682014 @default.
- W2103252468 countsByYear W21032524682015 @default.
- W2103252468 countsByYear W21032524682016 @default.
- W2103252468 countsByYear W21032524682017 @default.
- W2103252468 countsByYear W21032524682018 @default.
- W2103252468 countsByYear W21032524682019 @default.
- W2103252468 countsByYear W21032524682020 @default.
- W2103252468 countsByYear W21032524682021 @default.
- W2103252468 countsByYear W21032524682022 @default.
- W2103252468 countsByYear W21032524682023 @default.
- W2103252468 crossrefType "journal-article" @default.
- W2103252468 hasAuthorship W2103252468A5005804630 @default.
- W2103252468 hasAuthorship W2103252468A5018160190 @default.
- W2103252468 hasAuthorship W2103252468A5052017202 @default.
- W2103252468 hasAuthorship W2103252468A5063245254 @default.
- W2103252468 hasAuthorship W2103252468A5066461251 @default.
- W2103252468 hasAuthorship W2103252468A5079455479 @default.
- W2103252468 hasBestOaLocation W21032524681 @default.
- W2103252468 hasConcept C104317684 @default.
- W2103252468 hasConcept C124490489 @default.
- W2103252468 hasConcept C126322002 @default.
- W2103252468 hasConcept C127561419 @default.
- W2103252468 hasConcept C134018914 @default.
- W2103252468 hasConcept C179639408 @default.
- W2103252468 hasConcept C185592680 @default.
- W2103252468 hasConcept C2776151105 @default.
- W2103252468 hasConcept C2776914184 @default.
- W2103252468 hasConcept C2778653478 @default.
- W2103252468 hasConcept C2778838027 @default.
- W2103252468 hasConcept C2779524405 @default.