FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103261008> ?p ?o ?g. }

• W2103261008 endingPage "343" @default.
• W2103261008 startingPage "343" @default.
• W2103261008 abstract "Major depressive disorder (MDD) is a common and serious illness of our times, associated with monoamine deficiency in the brain. Moreover, increased levels of cortisol, possibly caused by stress, may be related to depression. In the treatment of MDD, the use of older antidepressants such as monoamine oxidase inhibitors and tricyclic antidepressants is decreasing rapidly, mainly due to their adverse effect profiles. In contrast, the use of serotonin reuptake inhibitors and newer antidepressants, which have dual modes of action such as inhibition of the serotonin and noradrenaline or dopamine reuptake, is increasing. Novel antidepressants have additive modes of action such as agomelatine, a potent agonist of melatonin receptors. Drugs in development for treatment of MDD include triple reuptake inhibitors, dual-acting serotonin reuptake inhibitors and histamine antagonists, and many more. Newer antidepressants have similar efficacy and in general good tolerability profiles. Nevertheless, compliance with treatment for MDD is poor and may contribute to treatment failure. Despite the broad spectrum of available antidepressants, there are still at least 30% of depressive patients who do not benefit from treatment. Therefore, new approaches in drug development are necessary and, according to current research developments, the future of antidepressant treatment may be promising." @default.
• W2103261008 created "2016-06-24" @default.
• W2103261008 creator A5012537111 @default.
• W2103261008 creator A5046050461 @default.
• W2103261008 creator A5071615050 @default.
• W2103261008 creator A5078793787 @default.
• W2103261008 date "2010-07-01" @default.
• W2103261008 modified "2023-09-26" @default.
• W2103261008 title "Getting the balance right: Established and emerging therapies for major depressive disorders" @default.
• W2103261008 cites W102145562 @default.
• W2103261008 cites W1233246898 @default.
• W2103261008 cites W1489185814 @default.
• W2103261008 cites W1546418958 @default.
• W2103261008 cites W1558899052 @default.
• W2103261008 cites W1587789767 @default.
• W2103261008 cites W1640525623 @default.
• W2103261008 cites W1655045766 @default.
• W2103261008 cites W1674319952 @default.
• W2103261008 cites W1688046947 @default.
• W2103261008 cites W1796828557 @default.
• W2103261008 cites W1896283473 @default.
• W2103261008 cites W1935246010 @default.
• W2103261008 cites W1963482722 @default.
• W2103261008 cites W1964022439 @default.
• W2103261008 cites W1964666670 @default.
• W2103261008 cites W1964827701 @default.
• W2103261008 cites W1966122783 @default.
• W2103261008 cites W1967365900 @default.
• W2103261008 cites W1969814360 @default.
• W2103261008 cites W1969966668 @default.
• W2103261008 cites W1970015406 @default.
• W2103261008 cites W1970635809 @default.
• W2103261008 cites W1971234076 @default.
• W2103261008 cites W1971880874 @default.
• W2103261008 cites W1973114177 @default.
• W2103261008 cites W1973239436 @default.
• W2103261008 cites W1976275668 @default.
• W2103261008 cites W1977708183 @default.
• W2103261008 cites W1980404010 @default.
• W2103261008 cites W1981693209 @default.
• W2103261008 cites W1982880546 @default.
• W2103261008 cites W1983822054 @default.
• W2103261008 cites W1984647264 @default.
• W2103261008 cites W1985193354 @default.
• W2103261008 cites W1986712720 @default.
• W2103261008 cites W1986887689 @default.
• W2103261008 cites W1987194328 @default.
• W2103261008 cites W1988773114 @default.
• W2103261008 cites W1991279188 @default.
• W2103261008 cites W1991625714 @default.
• W2103261008 cites W1992320105 @default.
• W2103261008 cites W1993067969 @default.
• W2103261008 cites W1993628347 @default.
• W2103261008 cites W1993690986 @default.
• W2103261008 cites W1994119877 @default.
• W2103261008 cites W1994256806 @default.
• W2103261008 cites W1997066747 @default.
• W2103261008 cites W2000591684 @default.
• W2103261008 cites W2002040612 @default.
• W2103261008 cites W2003027810 @default.
• W2103261008 cites W2003639118 @default.
• W2103261008 cites W2004365429 @default.
• W2103261008 cites W2005693447 @default.
• W2103261008 cites W2007708086 @default.
• W2103261008 cites W2007880575 @default.
• W2103261008 cites W2008973815 @default.
• W2103261008 cites W2009549897 @default.
• W2103261008 cites W2011828168 @default.
• W2103261008 cites W2015036418 @default.
• W2103261008 cites W2015383341 @default.
• W2103261008 cites W2016520193 @default.
• W2103261008 cites W2017145529 @default.
• W2103261008 cites W2018008180 @default.
• W2103261008 cites W2018425549 @default.
• W2103261008 cites W2018434620 @default.
• W2103261008 cites W2020739757 @default.
• W2103261008 cites W2022032351 @default.
• W2103261008 cites W2023205673 @default.
• W2103261008 cites W2023501491 @default.
• W2103261008 cites W2024231181 @default.
• W2103261008 cites W2024862901 @default.
• W2103261008 cites W2025050647 @default.
• W2103261008 cites W2025111977 @default.
• W2103261008 cites W2025678038 @default.
• W2103261008 cites W2025682675 @default.
• W2103261008 cites W2026657801 @default.
• W2103261008 cites W2026943977 @default.
• W2103261008 cites W2029297015 @default.
• W2103261008 cites W2029503234 @default.
• W2103261008 cites W2029951339 @default.
• W2103261008 cites W2032865655 @default.
• W2103261008 cites W2034366407 @default.
• W2103261008 cites W2035244689 @default.
• W2103261008 cites W2036744872 @default.
• W2103261008 cites W203770306 @default.
• W2103261008 cites W2037824539 @default.
• W2103261008 cites W2038208465 @default.
• W2103261008 cites W2038542976 @default.

• next