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- W2103261346 abstract "This review focuses on the emerging role of sulfated cyclodextrins in the capillary electrophoretic (CE) separation of chiral analytes. Since being introduced as enantioselective agents for CE in 1995, these anionic additives have continued to demonstrate remarkable application universality. The broad spectrum of chiral compounds successfully separated using this approach includes acidic, basic, neutral, and zwitterionic species. This impressive array of analyte structures is derived from a growing diversity of compound classes including pharmaceuticals, plant extracts, biomarkers, herbicides, alkaloids, fungicides, and metal ions. Moreover, literature reports highlight the minimal optimization required to achieve a successful separation. Based on these findings, sulfated cyclodextrins appear to be well suited for the development of a more universal, comprehensive separation strategy for chiral compounds. This review explores this proposition by beginning with the structure and migration properties of sulfated cyclodextrins, using applications to highlight the separating power of this technique and ending with a pragmatic, comprehensive separation strategy." @default.
- W2103261346 created "2016-06-24" @default.
- W2103261346 creator A5019848865 @default.
- W2103261346 creator A5076134953 @default.
- W2103261346 date "2003-01-01" @default.
- W2103261346 modified "2023-10-16" @default.
- W2103261346 title "Comprehensive strategy for chiral separations using sulfated cyclodextrins in capillary electrophoresis" @default.
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- W2103261346 doi "https://doi.org/10.1002/chir.10285" @default.
- W2103261346 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12923809" @default.
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