Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103284329> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2103284329 endingPage "62" @default.
- W2103284329 startingPage "62" @default.
- W2103284329 abstract "Intrahepatic cholestasis of pregnancy (ICP) is a peculiar disease in middle-late pregnancy with the pathological characteristics of hepatic capillary bile duct silts and is accompanied by clinical presentations of pruritus and bile acid (BA) elevation in serum. Maternal outcomes for patients diagnosed with ICP are usually good. However, fetal outcomes can be devastating with high frequencies of perinatal complications. Patients with ICP generally have an early delivery due to fetal complications. The current hypothesis is that ICP has higher frequencies of fetal complications due to high concentrations of BA which has toxic cellular effects to many organs. In lungs, it destroys the AT-II cells, decreasing phospholipids synthesis leading to the alveolar capillary permeability to increase and pulmonary surfactant to decrease. In heart, cholate can cross into the fetal compartment and causing fetal arrhythmias and decreased contractility. In the nervous system, high BAs can cause nerve cell denaturation and necrosis, mitochondria edema and membrane dissolve. In the placenta, high BA concentration can cause edema of the villous, decrease number of villous, intervillous thickening and balloon formation. EDITORIAL" @default.
- W2103284329 created "2016-06-24" @default.
- W2103284329 creator A5024468179 @default.
- W2103284329 creator A5078526337 @default.
- W2103284329 creator A5084175628 @default.
- W2103284329 date "2013-01-01" @default.
- W2103284329 modified "2023-09-26" @default.
- W2103284329 title "Why more attentions to fetus in cases of intrahepatic cholestasis of pregnancy?" @default.
- W2103284329 cites W1967722598 @default.
- W2103284329 cites W1975161517 @default.
- W2103284329 cites W1982410935 @default.
- W2103284329 cites W1982568464 @default.
- W2103284329 cites W2005793760 @default.
- W2103284329 cites W2024334265 @default.
- W2103284329 cites W2038899568 @default.
- W2103284329 cites W2045871245 @default.
- W2103284329 cites W2052407086 @default.
- W2103284329 cites W2053964379 @default.
- W2103284329 cites W2054096566 @default.
- W2103284329 cites W2055898569 @default.
- W2103284329 cites W2055915124 @default.
- W2103284329 cites W2060291029 @default.
- W2103284329 cites W2065523647 @default.
- W2103284329 cites W2072596683 @default.
- W2103284329 cites W2080131999 @default.
- W2103284329 cites W2082812258 @default.
- W2103284329 cites W2084918691 @default.
- W2103284329 cites W2123810061 @default.
- W2103284329 cites W2138520317 @default.
- W2103284329 cites W2331672470 @default.
- W2103284329 doi "https://doi.org/10.5317/wjog.v2.i4.62" @default.
- W2103284329 hasPublicationYear "2013" @default.
- W2103284329 type Work @default.
- W2103284329 sameAs 2103284329 @default.
- W2103284329 citedByCount "1" @default.
- W2103284329 countsByYear W21032843292014 @default.
- W2103284329 crossrefType "journal-article" @default.
- W2103284329 hasAuthorship W2103284329A5024468179 @default.
- W2103284329 hasAuthorship W2103284329A5078526337 @default.
- W2103284329 hasAuthorship W2103284329A5084175628 @default.
- W2103284329 hasBestOaLocation W21032843291 @default.
- W2103284329 hasConcept C126322002 @default.
- W2103284329 hasConcept C131872663 @default.
- W2103284329 hasConcept C172680121 @default.
- W2103284329 hasConcept C2778593092 @default.
- W2103284329 hasConcept C2779224579 @default.
- W2103284329 hasConcept C2779234561 @default.
- W2103284329 hasConcept C54355233 @default.
- W2103284329 hasConcept C71924100 @default.
- W2103284329 hasConcept C86803240 @default.
- W2103284329 hasConceptScore W2103284329C126322002 @default.
- W2103284329 hasConceptScore W2103284329C131872663 @default.
- W2103284329 hasConceptScore W2103284329C172680121 @default.
- W2103284329 hasConceptScore W2103284329C2778593092 @default.
- W2103284329 hasConceptScore W2103284329C2779224579 @default.
- W2103284329 hasConceptScore W2103284329C2779234561 @default.
- W2103284329 hasConceptScore W2103284329C54355233 @default.
- W2103284329 hasConceptScore W2103284329C71924100 @default.
- W2103284329 hasConceptScore W2103284329C86803240 @default.
- W2103284329 hasIssue "4" @default.
- W2103284329 hasLocation W21032843291 @default.
- W2103284329 hasOpenAccess W2103284329 @default.
- W2103284329 hasPrimaryLocation W21032843291 @default.
- W2103284329 hasRelatedWork W17254206 @default.
- W2103284329 hasRelatedWork W2035142208 @default.
- W2103284329 hasRelatedWork W2056752164 @default.
- W2103284329 hasRelatedWork W2246700988 @default.
- W2103284329 hasRelatedWork W2329728044 @default.
- W2103284329 hasRelatedWork W2334100510 @default.
- W2103284329 hasRelatedWork W2418060016 @default.
- W2103284329 hasRelatedWork W263426518 @default.
- W2103284329 hasRelatedWork W2759346835 @default.
- W2103284329 hasRelatedWork W3140323778 @default.
- W2103284329 hasVolume "2" @default.
- W2103284329 isParatext "false" @default.
- W2103284329 isRetracted "false" @default.
- W2103284329 magId "2103284329" @default.
- W2103284329 workType "article" @default.