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- W2103290735 abstract "The study of the processes relating glycobiology and cancer will have increased interest in coming years. To contribute to this trend the outcome of this work will be useful for investigations in glycobiology, using experimental methods exhibiting controlled carbohydrate composition, organization, and orientation, drawn from materials science and physics and that can be used in bioengineering and other technical areas in biology. In this work, the focus has been on physical studies of some members of the family of glycosaminoglycans and their role in cancer metastasis. The project studies the static adhesion of cancer cells to substrates functionalized with cell surface glycocalyx molecules and, in particular, in the interaction of heparan sulfate, keratan sulfate and chondroitin sulfates with the cells. Surface characterization techniques are used to analyze the structure of the polymeric brushes deposited on the substrates. The hypothesis that the adhesion of whole cancer cells to glysocaminoglycan substrates is a function of polysaccharide charge per dimer and chain length was proposed and tested. Part of the work has been dedicated to study the changes in the adhesion of tumor cells in the presence of heparanase, an enzyme expressed in the tumor cell surface." @default.
- W2103290735 created "2016-06-24" @default.
- W2103290735 creator A5045890871 @default.
- W2103290735 date "2005-01-01" @default.
- W2103290735 modified "2023-09-27" @default.
- W2103290735 title "Physical studies of glycosaminoglycans in relation to the adhesion properties of human cancer cells" @default.
- W2103290735 cites W1484403196 @default.
- W2103290735 cites W1491748226 @default.
- W2103290735 cites W1505352099 @default.
- W2103290735 cites W1526312778 @default.
- W2103290735 cites W1534818109 @default.
- W2103290735 cites W1539036257 @default.
- W2103290735 cites W1542334133 @default.
- W2103290735 cites W1544796307 @default.
- W2103290735 cites W1600054744 @default.
- W2103290735 cites W1600135572 @default.
- W2103290735 cites W1651280426 @default.
- W2103290735 cites W1656339735 @default.
- W2103290735 cites W1693086232 @default.
- W2103290735 cites W1751233322 @default.
- W2103290735 cites W1950519844 @default.
- W2103290735 cites W1964935114 @default.
- W2103290735 cites W1966126000 @default.
- W2103290735 cites W1967510196 @default.
- W2103290735 cites W1969324962 @default.
- W2103290735 cites W1969834700 @default.
- W2103290735 cites W1973758764 @default.
- W2103290735 cites W1977195767 @default.
- W2103290735 cites W1977837166 @default.
- W2103290735 cites W1982820514 @default.
- W2103290735 cites W1986750425 @default.
- W2103290735 cites W1987200074 @default.
- W2103290735 cites W1989676517 @default.
- W2103290735 cites W1991690944 @default.
- W2103290735 cites W2002613342 @default.
- W2103290735 cites W2002893780 @default.
- W2103290735 cites W2006186689 @default.
- W2103290735 cites W2007417175 @default.
- W2103290735 cites W2013858460 @default.
- W2103290735 cites W2015222290 @default.
- W2103290735 cites W2018848326 @default.
- W2103290735 cites W2018854273 @default.
- W2103290735 cites W2020887479 @default.
- W2103290735 cites W2024619901 @default.
- W2103290735 cites W2024879241 @default.
- W2103290735 cites W2025561491 @default.
- W2103290735 cites W2027789202 @default.
- W2103290735 cites W2028512526 @default.
- W2103290735 cites W2031532482 @default.
- W2103290735 cites W2034010375 @default.
- W2103290735 cites W2034248554 @default.
- W2103290735 cites W2034313331 @default.
- W2103290735 cites W2036475903 @default.
- W2103290735 cites W2040671013 @default.
- W2103290735 cites W2041420763 @default.
- W2103290735 cites W2047846174 @default.
- W2103290735 cites W2049667872 @default.
- W2103290735 cites W2052192720 @default.
- W2103290735 cites W2053123180 @default.
- W2103290735 cites W2053175158 @default.
- W2103290735 cites W2053907724 @default.
- W2103290735 cites W2054582185 @default.
- W2103290735 cites W2054649531 @default.
- W2103290735 cites W2056182522 @default.
- W2103290735 cites W2056409627 @default.
- W2103290735 cites W2058143304 @default.
- W2103290735 cites W2059614240 @default.
- W2103290735 cites W2060259421 @default.
- W2103290735 cites W2060529002 @default.
- W2103290735 cites W2060659946 @default.
- W2103290735 cites W2061776538 @default.
- W2103290735 cites W2064821140 @default.
- W2103290735 cites W2065405989 @default.
- W2103290735 cites W2066139999 @default.
- W2103290735 cites W2067376871 @default.
- W2103290735 cites W2072320731 @default.
- W2103290735 cites W2076788883 @default.
- W2103290735 cites W2076914900 @default.
- W2103290735 cites W2078559620 @default.
- W2103290735 cites W2080232145 @default.
- W2103290735 cites W2085524191 @default.
- W2103290735 cites W2089764248 @default.
- W2103290735 cites W2091307440 @default.
- W2103290735 cites W2091857312 @default.
- W2103290735 cites W2092405423 @default.
- W2103290735 cites W2093463100 @default.
- W2103290735 cites W2097053734 @default.
- W2103290735 cites W2099675490 @default.
- W2103290735 cites W2100959766 @default.
- W2103290735 cites W2101168661 @default.
- W2103290735 cites W2105301755 @default.
- W2103290735 cites W2111065678 @default.
- W2103290735 cites W2117899071 @default.
- W2103290735 cites W2123287179 @default.
- W2103290735 cites W2124614417 @default.
- W2103290735 cites W2131710476 @default.
- W2103290735 cites W2132001104 @default.
- W2103290735 cites W2132905138 @default.
- W2103290735 cites W2140074915 @default.
- W2103290735 cites W2144169464 @default.