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- W2103294892 abstract "Background: Drug-induced liver injury is increasing. This has multifactorial origin. Diabetic patients are more prone to such adverse effects since their multiple drugs are increasing in size and diversity. Several drugs used in diabetics are known to be hepatotoxic. In this case study, this issue is highlighted with special emphasis on presentation, diagnosis, management and prevention. Presentation: Fifty-one year old diabetic Arab male presented to the clinic with few days history of nausea, few episodes of vomiting and metallic taste. He had no history of abdominal pain, urinary symptoms or change in stool consistency, no history of reported allergies. The patient is a known case of myasthenia gravis of 12 years duration and type 2 diabetes of 13 years duration. He underwent thymomectomy as a treatment for his myasthenia gravis. The patient’s father is type 2 diabetic and his son is type 1 diabetic. He smokes few cigarettes per day and does not consume alcohol. The patient was on the following medications: Avandia 4mg since 18 months, Zocor 10mg since five years, Imuran (50100mg per day) and Prednisone (10-40mg per day) because of myasthenia gravis, Glucovance 5/500 mg twice a day for five months. The Zocor dose was increased to 20mg per day two weeks before presentation. On presentation the patient was afebrile, had a blood pressure of 120/80 and BMI of 29. He was alert, conscious and oriented. The patient was not jaundiced or dehydrated. No tremors were observed and abdominal examination was normal." @default.
- W2103294892 created "2016-06-24" @default.
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- W2103294892 date "2005-01-01" @default.
- W2103294892 modified "2023-09-27" @default.
- W2103294892 title "Case Study: Which is to be incriminated?" @default.
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