Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103295587> ?p ?o ?g. }
- W2103295587 endingPage "289" @default.
- W2103295587 startingPage "276" @default.
- W2103295587 abstract "Changing gain in a neuronal system has important functional consequences, but the underlying mechanisms have been elusive. Models have suggested a variety of neuronal and systems properties to accomplish gain control. Here, we show that the gain of the neuronal network underlying local bending behavior in leeches depends on widespread inhibition. Using behavioral analysis, intracellular recordings, and voltage-sensitive dye imaging, we compared the effects of blocking just the known lateral inhibition with blocking all GABAergic inhibition. This revealed an additional source of inhibition, which was widespread and increased in proportion to increasing stimulus intensity. In a model of the input/output functions of the three-layered local bending network, we showed that inhibiting all interneurons in proportion to the stimulus strength produces the experimentally observed change in gain. This relatively simple mechanism for controlling behavioral gain could be prevalent in vertebrate as well as invertebrate nervous systems." @default.
- W2103295587 created "2016-06-24" @default.
- W2103295587 creator A5009225650 @default.
- W2103295587 creator A5034448567 @default.
- W2103295587 creator A5064591109 @default.
- W2103295587 creator A5081136571 @default.
- W2103295587 date "2008-01-01" @default.
- W2103295587 modified "2023-10-16" @default.
- W2103295587 title "Widespread Inhibition Proportional to Excitation Controls the Gain of a Leech Behavioral Circuit" @default.
- W2103295587 cites W1480697866 @default.
- W2103295587 cites W1565932041 @default.
- W2103295587 cites W1594593166 @default.
- W2103295587 cites W1596185512 @default.
- W2103295587 cites W1607993187 @default.
- W2103295587 cites W1680669385 @default.
- W2103295587 cites W1795541753 @default.
- W2103295587 cites W1904163414 @default.
- W2103295587 cites W1926035353 @default.
- W2103295587 cites W1964008587 @default.
- W2103295587 cites W1964031992 @default.
- W2103295587 cites W1967538789 @default.
- W2103295587 cites W1973327463 @default.
- W2103295587 cites W1986858494 @default.
- W2103295587 cites W1987159148 @default.
- W2103295587 cites W1992542014 @default.
- W2103295587 cites W1992744745 @default.
- W2103295587 cites W1993938369 @default.
- W2103295587 cites W1999759596 @default.
- W2103295587 cites W2002297258 @default.
- W2103295587 cites W2007221253 @default.
- W2103295587 cites W2007946757 @default.
- W2103295587 cites W2018197873 @default.
- W2103295587 cites W2023674803 @default.
- W2103295587 cites W2025102634 @default.
- W2103295587 cites W2027510518 @default.
- W2103295587 cites W2032774941 @default.
- W2103295587 cites W2032931981 @default.
- W2103295587 cites W2038718814 @default.
- W2103295587 cites W2040663063 @default.
- W2103295587 cites W2041461999 @default.
- W2103295587 cites W2054316680 @default.
- W2103295587 cites W2058216506 @default.
- W2103295587 cites W2061512758 @default.
- W2103295587 cites W2067501282 @default.
- W2103295587 cites W2071986958 @default.
- W2103295587 cites W2090184352 @default.
- W2103295587 cites W2091985726 @default.
- W2103295587 cites W2098118593 @default.
- W2103295587 cites W2099441089 @default.
- W2103295587 cites W2099525751 @default.
- W2103295587 cites W2100438317 @default.
- W2103295587 cites W2101231686 @default.
- W2103295587 cites W2104536300 @default.
- W2103295587 cites W2106700142 @default.
- W2103295587 cites W2107650772 @default.
- W2103295587 cites W2112399590 @default.
- W2103295587 cites W2118015362 @default.
- W2103295587 cites W2125733184 @default.
- W2103295587 cites W2134484803 @default.
- W2103295587 cites W2135370405 @default.
- W2103295587 cites W2137836504 @default.
- W2103295587 cites W2139326454 @default.
- W2103295587 cites W2149296794 @default.
- W2103295587 cites W2152621999 @default.
- W2103295587 cites W2157126630 @default.
- W2103295587 cites W2166327688 @default.
- W2103295587 cites W2166740761 @default.
- W2103295587 cites W2169534307 @default.
- W2103295587 cites W2172099747 @default.
- W2103295587 cites W2212384750 @default.
- W2103295587 cites W2270283363 @default.
- W2103295587 cites W23745746 @default.
- W2103295587 cites W3162520581 @default.
- W2103295587 cites W2088553406 @default.
- W2103295587 doi "https://doi.org/10.1016/j.neuron.2007.11.028" @default.
- W2103295587 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4084705" @default.
- W2103295587 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18215624" @default.
- W2103295587 hasPublicationYear "2008" @default.
- W2103295587 type Work @default.
- W2103295587 sameAs 2103295587 @default.
- W2103295587 citedByCount "59" @default.
- W2103295587 countsByYear W21032955872012 @default.
- W2103295587 countsByYear W21032955872013 @default.
- W2103295587 countsByYear W21032955872014 @default.
- W2103295587 countsByYear W21032955872015 @default.
- W2103295587 countsByYear W21032955872016 @default.
- W2103295587 countsByYear W21032955872017 @default.
- W2103295587 countsByYear W21032955872018 @default.
- W2103295587 countsByYear W21032955872020 @default.
- W2103295587 countsByYear W21032955872021 @default.
- W2103295587 countsByYear W21032955872022 @default.
- W2103295587 countsByYear W21032955872023 @default.
- W2103295587 crossrefType "journal-article" @default.
- W2103295587 hasAuthorship W2103295587A5009225650 @default.
- W2103295587 hasAuthorship W2103295587A5034448567 @default.
- W2103295587 hasAuthorship W2103295587A5064591109 @default.
- W2103295587 hasAuthorship W2103295587A5081136571 @default.
- W2103295587 hasBestOaLocation W21032955871 @default.