FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103301134> ?p ?o ?g. }

• W2103301134 endingPage "5779" @default.
• W2103301134 startingPage "5771" @default.
• W2103301134 abstract "Ag-presenting dendritic cells present viral Ags to T cells after uptake of apoptotic bodies derived from virus-infected cells in vitro. However, it is unclear whether apoptotic virus-infected cells are capable of generating immunity in vivo. In this study, we show that inoculation of mice with apoptotic HIV-1/murine leukemia virus (MuLV)-infected cells induces HIV-1-specific immunity. Immunization with apoptotic HIV-1/MuLV-infected syngeneic splenocytes resulted in strong Nef-specific CD8(+) T cell proliferation and p24-induced CD4(+) and CD8(+) T cell proliferation as well as IFN-gamma production. In addition, systemic IgG and IgA as well as mucosa-associated IgA responses were generated. Moreover, mice vaccinated with apoptotic HIV-1/MuLV cells were protected against challenge with live HIV-1/MuLV-infected cells, whereas mice vaccinated with apoptotic noninfected or MuLV-infected splenocytes remained susceptible to HIV-1/MuLV. These data show that i.p. immunization with apoptotic HIV-1-infected cells induces high levels of HIV-1-specific systemic immunity, primes for mucosal immunity, and induces protection against challenge with live HIV-1-infected cells in mice. These findings may have implications for the development of therapeutic and prophylactic HIV-1 vaccines." @default.
• W2103301134 created "2016-06-24" @default.
• W2103301134 creator A5004527390 @default.
• W2103301134 creator A5009644444 @default.
• W2103301134 creator A5018768648 @default.
• W2103301134 creator A5027200440 @default.
• W2103301134 creator A5036153902 @default.
• W2103301134 creator A5056059593 @default.
• W2103301134 creator A5087134604 @default.
• W2103301134 date "2002-11-15" @default.
• W2103301134 modified "2023-10-17" @default.
• W2103301134 title "Induction of HIV-1-Specific Immunity After Vaccination with Apoptotic HIV-1/Murine Leukemia Virus-Infected Cells" @default.
• W2103301134 cites W1535836957 @default.
• W2103301134 cites W1561591381 @default.
• W2103301134 cites W1574561647 @default.
• W2103301134 cites W1576582350 @default.
• W2103301134 cites W1585454314 @default.
• W2103301134 cites W1589945128 @default.
• W2103301134 cites W1596938308 @default.
• W2103301134 cites W1635348995 @default.
• W2103301134 cites W1644579564 @default.
• W2103301134 cites W1656708631 @default.
• W2103301134 cites W1663973802 @default.
• W2103301134 cites W1837913556 @default.
• W2103301134 cites W1931655778 @default.
• W2103301134 cites W1959432277 @default.
• W2103301134 cites W1964003691 @default.
• W2103301134 cites W1964360556 @default.
• W2103301134 cites W1971160396 @default.
• W2103301134 cites W1981932944 @default.
• W2103301134 cites W1989670405 @default.
• W2103301134 cites W1991293757 @default.
• W2103301134 cites W1994040691 @default.
• W2103301134 cites W1994993383 @default.
• W2103301134 cites W1995667011 @default.
• W2103301134 cites W1998371035 @default.
• W2103301134 cites W1998426346 @default.
• W2103301134 cites W2002657509 @default.
• W2103301134 cites W2018060065 @default.
• W2103301134 cites W2034219867 @default.
• W2103301134 cites W2036893513 @default.
• W2103301134 cites W2041971745 @default.
• W2103301134 cites W2062813847 @default.
• W2103301134 cites W2069428724 @default.
• W2103301134 cites W2077721338 @default.
• W2103301134 cites W2084454379 @default.
• W2103301134 cites W2088972036 @default.
• W2103301134 cites W2112222308 @default.
• W2103301134 cites W2112810894 @default.
• W2103301134 cites W2112940264 @default.
• W2103301134 cites W2115730927 @default.
• W2103301134 cites W2118530404 @default.
• W2103301134 cites W2122231405 @default.
• W2103301134 cites W2123076394 @default.
• W2103301134 cites W2135073267 @default.
• W2103301134 cites W2141750611 @default.
• W2103301134 cites W2151303894 @default.
• W2103301134 cites W2156110652 @default.
• W2103301134 cites W2158500407 @default.
• W2103301134 cites W2159185426 @default.
• W2103301134 cites W2166378622 @default.
• W2103301134 cites W2166584906 @default.
• W2103301134 cites W2322415950 @default.
• W2103301134 cites W4313331874 @default.
• W2103301134 doi "https://doi.org/10.4049/jimmunol.169.10.5771" @default.
• W2103301134 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12421957" @default.
• W2103301134 hasPublicationYear "2002" @default.
• W2103301134 type Work @default.
• W2103301134 sameAs 2103301134 @default.
• W2103301134 citedByCount "39" @default.
• W2103301134 countsByYear W21033011342012 @default.
• W2103301134 countsByYear W21033011342013 @default.
• W2103301134 countsByYear W21033011342014 @default.
• W2103301134 crossrefType "journal-article" @default.
• W2103301134 hasAuthorship W2103301134A5004527390 @default.
• W2103301134 hasAuthorship W2103301134A5009644444 @default.
• W2103301134 hasAuthorship W2103301134A5018768648 @default.
• W2103301134 hasAuthorship W2103301134A5027200440 @default.
• W2103301134 hasAuthorship W2103301134A5036153902 @default.
• W2103301134 hasAuthorship W2103301134A5056059593 @default.
• W2103301134 hasAuthorship W2103301134A5087134604 @default.
• W2103301134 hasBestOaLocation W21033011341 @default.
• W2103301134 hasConcept C159047783 @default.
• W2103301134 hasConcept C167672396 @default.
• W2103301134 hasConcept C189976730 @default.
• W2103301134 hasConcept C190283241 @default.
• W2103301134 hasConcept C203014093 @default.
• W2103301134 hasConcept C2522874641 @default.
• W2103301134 hasConcept C2779341262 @default.
• W2103301134 hasConcept C2779562191 @default.
• W2103301134 hasConcept C2780801004 @default.
• W2103301134 hasConcept C55493867 @default.
• W2103301134 hasConcept C86803240 @default.
• W2103301134 hasConcept C8891405 @default.
• W2103301134 hasConceptScore W2103301134C159047783 @default.
• W2103301134 hasConceptScore W2103301134C167672396 @default.
• W2103301134 hasConceptScore W2103301134C189976730 @default.
• W2103301134 hasConceptScore W2103301134C190283241 @default.

• next