FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103304416> ?p ?o ?g. }

• W2103304416 endingPage "807" @default.
• W2103304416 startingPage "799" @default.
• W2103304416 abstract "Bone is the second most frequent target of distant metastases in patients with differentiated thyroid cancer, and such forms carry a very poor prognosis. The impact of (131)I therapy in this setting is controversial. We describe the diagnostic circumstances and outcome of patients with bone metastases recently managed in two institutions. Among 921 consecutive thyroid cancer patients who had total thyroidectomy and (131)I ablation between January 2000 and December 2004 and who were subsequently monitored, bone metastases had been diagnosed in 16 patients. In three cases, the bone metastases were non-functioning (negative (131)I uptake) . These patients were treated with surgery and radiotherapy but progressed rapidly. The other 13 patients had functioning (positive (131)I uptake) bone metastases. In five of them, thyroid cancer was revealed by signs of distant involvement (bone pain, n = 4; dyspnea, n = 1). The bone metastases progressed in these five patients, despite local therapy and multiple courses of (131)I. The bone metastases in the remaining eight patients were discovered on the post-surgery (131)I therapy scan. Complementary radiological studies were negative except in one patient in whom one of the metastases (a 5 mm lesion of the right humerus) was visible on magnetic resonance imaging (MRI). Six of these patients showed a good response to (131)I therapy, with (131)I uptake and Tg levels becoming undetectable or showing a sharp fall. One patient refused (131)I therapy; bone metastases became visible on MRI within 1 year and the Tg level rose tenfold. The disease progressed in one patient despite (131)I therapy. Post-surgical (131)I ablation can contribute to early detection of bone metastases at a time when the Tg level may be only moderately elevated, when other radiological studies are negative, and when the disease is potentially curable by (131)I therapy." @default.
• W2103304416 created "2016-06-24" @default.
• W2103304416 creator A5020205103 @default.
• W2103304416 creator A5025613428 @default.
• W2103304416 creator A5026852302 @default.
• W2103304416 creator A5030039930 @default.
• W2103304416 creator A5035740196 @default.
• W2103304416 creator A5042373507 @default.
• W2103304416 creator A5054802025 @default.
• W2103304416 creator A5058319008 @default.
• W2103304416 creator A5064018502 @default.
• W2103304416 creator A5081294020 @default.
• W2103304416 date "2007-09-01" @default.
• W2103304416 modified "2023-10-05" @default.
• W2103304416 title "Bone metastases of differentiated thyroid cancer: impact of early 131I-based detection on outcome" @default.
• W2103304416 cites W1834282953 @default.
• W2103304416 cites W1972980393 @default.
• W2103304416 cites W1995643033 @default.
• W2103304416 cites W2009925064 @default.
• W2103304416 cites W2022699230 @default.
• W2103304416 cites W2027611938 @default.
• W2103304416 cites W2027713082 @default.
• W2103304416 cites W2040642592 @default.
• W2103304416 cites W2045367553 @default.
• W2103304416 cites W2050962190 @default.
• W2103304416 cites W2087440541 @default.
• W2103304416 cites W2091923260 @default.
• W2103304416 cites W2114374078 @default.
• W2103304416 cites W2115643427 @default.
• W2103304416 cites W2132185197 @default.
• W2103304416 cites W2138825979 @default.
• W2103304416 cites W2139809746 @default.
• W2103304416 cites W2156954509 @default.
• W2103304416 cites W2159410361 @default.
• W2103304416 cites W2170906062 @default.
• W2103304416 cites W2323016503 @default.
• W2103304416 cites W2403993630 @default.
• W2103304416 cites W72682960 @default.
• W2103304416 doi "https://doi.org/10.1677/erc-07-0120" @default.
• W2103304416 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17914109" @default.
• W2103304416 hasPublicationYear "2007" @default.
• W2103304416 type Work @default.
• W2103304416 sameAs 2103304416 @default.
• W2103304416 citedByCount "63" @default.
• W2103304416 countsByYear W21033044162012 @default.
• W2103304416 countsByYear W21033044162013 @default.
• W2103304416 countsByYear W21033044162014 @default.
• W2103304416 countsByYear W21033044162015 @default.
• W2103304416 countsByYear W21033044162016 @default.
• W2103304416 countsByYear W21033044162017 @default.
• W2103304416 countsByYear W21033044162018 @default.
• W2103304416 countsByYear W21033044162019 @default.
• W2103304416 countsByYear W21033044162021 @default.
• W2103304416 countsByYear W21033044162022 @default.
• W2103304416 countsByYear W21033044162023 @default.
• W2103304416 crossrefType "journal-article" @default.
• W2103304416 hasAuthorship W2103304416A5020205103 @default.
• W2103304416 hasAuthorship W2103304416A5025613428 @default.
• W2103304416 hasAuthorship W2103304416A5026852302 @default.
• W2103304416 hasAuthorship W2103304416A5030039930 @default.
• W2103304416 hasAuthorship W2103304416A5035740196 @default.
• W2103304416 hasAuthorship W2103304416A5042373507 @default.
• W2103304416 hasAuthorship W2103304416A5054802025 @default.
• W2103304416 hasAuthorship W2103304416A5058319008 @default.
• W2103304416 hasAuthorship W2103304416A5064018502 @default.
• W2103304416 hasAuthorship W2103304416A5081294020 @default.
• W2103304416 hasBestOaLocation W21033044161 @default.
• W2103304416 hasConcept C121608353 @default.
• W2103304416 hasConcept C126322002 @default.
• W2103304416 hasConcept C126838900 @default.
• W2103304416 hasConcept C141071460 @default.
• W2103304416 hasConcept C143409427 @default.
• W2103304416 hasConcept C2777074255 @default.
• W2103304416 hasConcept C2777783956 @default.
• W2103304416 hasConcept C2779013556 @default.
• W2103304416 hasConcept C2779761222 @default.
• W2103304416 hasConcept C509974204 @default.
• W2103304416 hasConcept C526584372 @default.
• W2103304416 hasConcept C71924100 @default.
• W2103304416 hasConceptScore W2103304416C121608353 @default.
• W2103304416 hasConceptScore W2103304416C126322002 @default.
• W2103304416 hasConceptScore W2103304416C126838900 @default.
• W2103304416 hasConceptScore W2103304416C141071460 @default.
• W2103304416 hasConceptScore W2103304416C143409427 @default.
• W2103304416 hasConceptScore W2103304416C2777074255 @default.
• W2103304416 hasConceptScore W2103304416C2777783956 @default.
• W2103304416 hasConceptScore W2103304416C2779013556 @default.
• W2103304416 hasConceptScore W2103304416C2779761222 @default.
• W2103304416 hasConceptScore W2103304416C509974204 @default.
• W2103304416 hasConceptScore W2103304416C526584372 @default.
• W2103304416 hasConceptScore W2103304416C71924100 @default.
• W2103304416 hasIssue "3" @default.
• W2103304416 hasLocation W21033044161 @default.
• W2103304416 hasLocation W21033044162 @default.
• W2103304416 hasOpenAccess W2103304416 @default.
• W2103304416 hasPrimaryLocation W21033044161 @default.
• W2103304416 hasRelatedWork W2003938723 @default.
• W2103304416 hasRelatedWork W2047967234 @default.

• next