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• W2103362802 endingPage "F1335" @default.
• W2103362802 startingPage "F1324" @default.
• W2103362802 abstract "Spinal cord-mediated cross-organ sensitization between the uterus and the lower urinary tract may underlie the high concurrence of obstetrical/gynecological inflammation and chronic pelvic pain syndrome characterized by urogenital pain. However, the neural pathway and the neurotransmitters involved are still unknown. We tested the hypothesis that the excitation of capsaicin-sensitive primary afferent fibers arising from the uterus through the stimulation of transient receptor potential vanilloid 1 (TRPV 1 ) induces cross-organ sensitization on the pelvic-urethra reflex activity. Capsaicin (1–1,000 μM, 0.05 ml) was instilled into the uterus to induce cross-organ reflex sensitization. Activation of capsaicin-sensitive primary afferent fibers by capsaicin instillation into the uterine horn sensitized the pelvic-urethra reflex activity that was reversed by an intrauterine pretreatment with capsaizepine, a TRPV 1 -selective antagonist. Intrathecal injection of AP5, a glutamatergic N-methyl-d-aspartate (NMDA) antagonist, and Co-101244, an NMDA NR2B-selective antagonist, both abolished the cross-organ reflex sensitization caused by capsaicin instillation. These results demonstrated that TRPV 1 plays a crucial role in contributing to the capsaicin-sensitive primary afferent fibers mediating the glutamatergic NMDA-dependent cross-organ sensitization between the uterus and the lower urinary tract when there is a tissue injury." @default.
• W2103362802 created "2016-06-24" @default.
• W2103362802 creator A5012764564 @default.
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• W2103362802 creator A5090573384 @default.
• W2103362802 date "2008-11-01" @default.
• W2103362802 modified "2023-10-18" @default.
• W2103362802 title "TRPV₁ mediates the uterine capsaicin-induced NMDA NR2B-dependent cross-organ reflex sensitization in anesthetized rats" @default.
• W2103362802 cites W1502599914 @default.
• W2103362802 cites W1543782039 @default.
• W2103362802 cites W1796360274 @default.
• W2103362802 cites W1863375292 @default.
• W2103362802 cites W1963789935 @default.
• W2103362802 cites W1969400739 @default.
• W2103362802 cites W1969730957 @default.
• W2103362802 cites W1971566600 @default.
• W2103362802 cites W1973806783 @default.
• W2103362802 cites W1974543579 @default.
• W2103362802 cites W1985569288 @default.
• W2103362802 cites W1985745957 @default.
• W2103362802 cites W1986599194 @default.
• W2103362802 cites W1988059170 @default.
• W2103362802 cites W1988375390 @default.
• W2103362802 cites W1990442137 @default.
• W2103362802 cites W2003372927 @default.
• W2103362802 cites W2004169894 @default.
• W2103362802 cites W2007049211 @default.
• W2103362802 cites W2015191108 @default.
• W2103362802 cites W2019659882 @default.
• W2103362802 cites W2020681571 @default.
• W2103362802 cites W2022898812 @default.
• W2103362802 cites W2023003153 @default.
• W2103362802 cites W2024255262 @default.
• W2103362802 cites W2024420229 @default.
• W2103362802 cites W2029184841 @default.
• W2103362802 cites W2037082355 @default.
• W2103362802 cites W2039101107 @default.
• W2103362802 cites W2040927502 @default.
• W2103362802 cites W2041400100 @default.
• W2103362802 cites W2042695337 @default.
• W2103362802 cites W2045592577 @default.
• W2103362802 cites W2048050019 @default.
• W2103362802 cites W2050781058 @default.
• W2103362802 cites W2052774071 @default.
• W2103362802 cites W2054661844 @default.
• W2103362802 cites W2055890544 @default.
• W2103362802 cites W2057439534 @default.
• W2103362802 cites W2060142554 @default.
• W2103362802 cites W2060449072 @default.
• W2103362802 cites W2063102563 @default.
• W2103362802 cites W2063280749 @default.
• W2103362802 cites W2065898415 @default.
• W2103362802 cites W2071564618 @default.
• W2103362802 cites W2071819583 @default.
• W2103362802 cites W2074319379 @default.
• W2103362802 cites W2076438539 @default.
• W2103362802 cites W2080519186 @default.
• W2103362802 cites W2084180916 @default.
• W2103362802 cites W2086780780 @default.
• W2103362802 cites W2097517640 @default.
• W2103362802 cites W2098518537 @default.
• W2103362802 cites W2098743691 @default.
• W2103362802 cites W2100459283 @default.
• W2103362802 cites W2107489805 @default.
• W2103362802 cites W2107795177 @default.
• W2103362802 cites W2107988902 @default.
• W2103362802 cites W2112286648 @default.
• W2103362802 cites W2113920810 @default.
• W2103362802 cites W2116635659 @default.
• W2103362802 cites W2118803844 @default.
• W2103362802 cites W2122081946 @default.
• W2103362802 cites W2125019803 @default.
• W2103362802 cites W2125649919 @default.
• W2103362802 cites W2126245788 @default.
• W2103362802 cites W2127227569 @default.
• W2103362802 cites W2127246176 @default.
• W2103362802 cites W2127706439 @default.
• W2103362802 cites W2129560765 @default.
• W2103362802 cites W2129597960 @default.
• W2103362802 cites W2130666985 @default.
• W2103362802 cites W2132829674 @default.
• W2103362802 cites W2134742719 @default.
• W2103362802 cites W2148759073 @default.
• W2103362802 cites W2154152759 @default.
• W2103362802 cites W2155421623 @default.
• W2103362802 cites W2162373360 @default.
• W2103362802 cites W2164676774 @default.
• W2103362802 cites W2170541300 @default.
• W2103362802 cites W2171585176 @default.
• W2103362802 cites W2338712263 @default.
• W2103362802 cites W4230889514 @default.
• W2103362802 cites W4238011899 @default.

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