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- W2103402160 abstract "Abstract The evolution of microorganism defense systems has led to intensive searches for new drugs extracted from various natural products to fight microbial infections. This study evaluated the antibacterial and antifungal activity of Lygodium venustum, a climbing fern. A phytochemical screening was performed using ethanol extract from leaves of L. venustum (EELV), detecting the presence of phenols, tannins, flavonoids and alkaloids. The test of Minimal Inhibitory Concentration (MIC) against Escherichia coli, Staphyloccocus aureus, Pseudomonas aeruginosa, Candida albicans, C. krusei and C. tropicalis was evaluated using the microdilution method, resulting in inhibitory concentrations ≥ 1024 µg/mL. Using a subinhibitory concentration of 128 µg/mL of EELV, the modulatory potential of the extract was tested against multidrug-resistant clinical isolates, resulting in synergism when combined with Gentamicin and actually altering the phenotype of S. aureus from sensitive to resistant. The extract also increas..." @default.
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- W2103402160 date "2012-04-01" @default.
- W2103402160 modified "2023-09-26" @default.
- W2103402160 title "Antimicrobial and Modulatory Activity of Ethanol Extract of the Leaves from Lygodium venustum SW" @default.
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- W2103402160 doi "https://doi.org/10.1640/0002-8444-102.2.154" @default.
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