FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103407511> ?p ?o ?g. }

• W2103407511 endingPage "12" @default.
• W2103407511 startingPage "3" @default.
• W2103407511 abstract "Acoustic startle response (ASR) is a defensive reflex that occurs shortly after presentation of a brief intense acoustic stimulus. It consists of a sudden contraction of facial and skeletal muscle. ASR in rodents is a gross vibration-like movement of the body that is easy to elicit, record, and analyze quantitatively. It can also be used as a reliable and sensitive measure of physiological mechanism of developmental toxicity. The basic neural mechanisms of ASR have been elucidated. The cochlear nucleus and the reticular nucleus of pons are essential to the induction and regulation of ASR amplitude. Fear or anxiety augments ASR (fear potentiation) and functionally involves amygdala. A brief presentation of a weak acoustic stimulus shortly before the presentation of a startling stimulus suppresses ASR (prepulse inhibition). Prepulse inhibition is thought to be regulated by the dopaminergic mesolimbic system. Taken together, these phenomena suggest the use of ASR as a means of modeling anxiety/fear and the sensorymotor abnormalities that may present themselves in a condition such as schizophrenia. In this review, the fundamental behavioral and neural features of ASR are described and major findings in connection with the toxicology of ASR are reviewed. Finally, the significance of ASR in the study of developmental toxicology including behavioral teratology is discussed. Key words: acoustic startle response, fear potentiation, prepulse inhibition, developmental toxicology, behavioral teratology" @default.
• W2103407511 created "2016-06-24" @default.
• W2103407511 creator A5091270672 @default.
• W2103407511 date "2008-06-28" @default.
• W2103407511 modified "2023-09-24" @default.
• W2103407511 title "Acoustic Startle Response in the Study of Developmental Toxicity" @default.
• W2103407511 cites W1545972494 @default.
• W2103407511 cites W1895646316 @default.
• W2103407511 cites W1966925780 @default.
• W2103407511 cites W1967437195 @default.
• W2103407511 cites W1972662179 @default.
• W2103407511 cites W1974460181 @default.
• W2103407511 cites W1974675807 @default.
• W2103407511 cites W1975838690 @default.
• W2103407511 cites W1977232166 @default.
• W2103407511 cites W1978614486 @default.
• W2103407511 cites W1984455450 @default.
• W2103407511 cites W1985264935 @default.
• W2103407511 cites W1986487757 @default.
• W2103407511 cites W1990267093 @default.
• W2103407511 cites W1994667451 @default.
• W2103407511 cites W1997223078 @default.
• W2103407511 cites W1998141074 @default.
• W2103407511 cites W1999643558 @default.
• W2103407511 cites W2001529605 @default.
• W2103407511 cites W2003743794 @default.
• W2103407511 cites W2004074687 @default.
• W2103407511 cites W2008126685 @default.
• W2103407511 cites W2008415235 @default.
• W2103407511 cites W2013306798 @default.
• W2103407511 cites W2017269874 @default.
• W2103407511 cites W2018806863 @default.
• W2103407511 cites W2028154685 @default.
• W2103407511 cites W2032075180 @default.
• W2103407511 cites W2032829083 @default.
• W2103407511 cites W2034101922 @default.
• W2103407511 cites W2035749259 @default.
• W2103407511 cites W2045161094 @default.
• W2103407511 cites W2046903898 @default.
• W2103407511 cites W2048880280 @default.
• W2103407511 cites W2051962625 @default.
• W2103407511 cites W2054033141 @default.
• W2103407511 cites W2055171682 @default.
• W2103407511 cites W2060884332 @default.
• W2103407511 cites W2061748344 @default.
• W2103407511 cites W2069292064 @default.
• W2103407511 cites W2075842142 @default.
• W2103407511 cites W2079859358 @default.
• W2103407511 cites W2080611343 @default.
• W2103407511 cites W2082636144 @default.
• W2103407511 cites W2085448164 @default.
• W2103407511 cites W2092526926 @default.
• W2103407511 cites W2093070630 @default.
• W2103407511 cites W2112618140 @default.
• W2103407511 cites W2131432522 @default.
• W2103407511 cites W4243250297 @default.
• W2103407511 doi "https://doi.org/10.1111/j.1741-4520.1999.tb00985.x" @default.
• W2103407511 hasPublicationYear "2008" @default.
• W2103407511 type Work @default.
• W2103407511 sameAs 2103407511 @default.
• W2103407511 citedByCount "0" @default.
• W2103407511 crossrefType "journal-article" @default.
• W2103407511 hasAuthorship W2103407511A5091270672 @default.
• W2103407511 hasBestOaLocation W21034075111 @default.
• W2103407511 hasConcept C118552586 @default.
• W2103407511 hasConcept C137431309 @default.
• W2103407511 hasConcept C141421786 @default.
• W2103407511 hasConcept C15744967 @default.
• W2103407511 hasConcept C16837860 @default.
• W2103407511 hasConcept C169760540 @default.
• W2103407511 hasConcept C180747234 @default.
• W2103407511 hasConcept C23332255 @default.
• W2103407511 hasConcept C2776412080 @default.
• W2103407511 hasConcept C2777845764 @default.
• W2103407511 hasConcept C2779144063 @default.
• W2103407511 hasConcept C2779918689 @default.
• W2103407511 hasConcept C2909172351 @default.
• W2103407511 hasConcept C2910993415 @default.
• W2103407511 hasConcept C548259974 @default.
• W2103407511 hasConcept C71924100 @default.
• W2103407511 hasConcept C83974742 @default.
• W2103407511 hasConceptScore W2103407511C118552586 @default.
• W2103407511 hasConceptScore W2103407511C137431309 @default.
• W2103407511 hasConceptScore W2103407511C141421786 @default.
• W2103407511 hasConceptScore W2103407511C15744967 @default.
• W2103407511 hasConceptScore W2103407511C16837860 @default.
• W2103407511 hasConceptScore W2103407511C169760540 @default.
• W2103407511 hasConceptScore W2103407511C180747234 @default.
• W2103407511 hasConceptScore W2103407511C23332255 @default.
• W2103407511 hasConceptScore W2103407511C2776412080 @default.
• W2103407511 hasConceptScore W2103407511C2777845764 @default.
• W2103407511 hasConceptScore W2103407511C2779144063 @default.
• W2103407511 hasConceptScore W2103407511C2779918689 @default.
• W2103407511 hasConceptScore W2103407511C2909172351 @default.
• W2103407511 hasConceptScore W2103407511C2910993415 @default.
• W2103407511 hasConceptScore W2103407511C548259974 @default.
• W2103407511 hasConceptScore W2103407511C71924100 @default.
• W2103407511 hasConceptScore W2103407511C83974742 @default.

• next