Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103451732> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2103451732 endingPage "142" @default.
- W2103451732 startingPage "138" @default.
- W2103451732 abstract "I was honored to be the keynote speaker at the 30th Annual Society of Toxicologic Pathology Symposium “Toxicologic Pathology and the Immune System.” I had the opportunity to reminisce about events in the 1970s that set the stage for the birth and subsequent growth of the field of immunotoxicology and to summarize my research career that has spanned the past 40 years as well. An initial focus on the immunotoxicity of pentachlorophenol led my laboratory into the aryl hydrocarbon receptor (AHR) field and the study of its most potent ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). My research career has been devoted to trying to elucidate the immunological basis of TCDD’s profound immunosuppressive activity that is mediated by activation of AHR. In recent years, my laboratory has focused on the role of CD4 + T cells as targets of TCDD, and we were the first to describe the induction of AHR-dependent regulatory T cells (Tregs). The ability to induce Tregs using an exogenous AHR ligand to activate the AHR-Treg pathway represents a novel approach to the prevention and/or treatment of autoimmune disease. We are currently searching for such ligands." @default.
- W2103451732 created "2016-06-24" @default.
- W2103451732 creator A5088955577 @default.
- W2103451732 date "2011-11-16" @default.
- W2103451732 modified "2023-10-18" @default.
- W2103451732 title "TCDD: An Environmental Immunotoxicant Reveals a Novel Pathway of Immunoregulation—A 30-Year Odyssey" @default.
- W2103451732 cites W1485246802 @default.
- W2103451732 cites W1577296862 @default.
- W2103451732 cites W1595242735 @default.
- W2103451732 cites W1644952681 @default.
- W2103451732 cites W1933952629 @default.
- W2103451732 cites W1935479846 @default.
- W2103451732 cites W1967223275 @default.
- W2103451732 cites W1980690619 @default.
- W2103451732 cites W1985096197 @default.
- W2103451732 cites W1989564414 @default.
- W2103451732 cites W1993207988 @default.
- W2103451732 cites W2004522121 @default.
- W2103451732 cites W2012989963 @default.
- W2103451732 cites W2021713059 @default.
- W2103451732 cites W2022773559 @default.
- W2103451732 cites W2052006922 @default.
- W2103451732 cites W2067780236 @default.
- W2103451732 cites W2069975493 @default.
- W2103451732 cites W2076713824 @default.
- W2103451732 cites W2081913057 @default.
- W2103451732 cites W2082354876 @default.
- W2103451732 cites W2085592918 @default.
- W2103451732 cites W2106999205 @default.
- W2103451732 cites W2112737139 @default.
- W2103451732 cites W2122371014 @default.
- W2103451732 cites W2133795774 @default.
- W2103451732 cites W2149558380 @default.
- W2103451732 cites W2156884339 @default.
- W2103451732 doi "https://doi.org/10.1177/0192623311427710" @default.
- W2103451732 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22089840" @default.
- W2103451732 hasPublicationYear "2011" @default.
- W2103451732 type Work @default.
- W2103451732 sameAs 2103451732 @default.
- W2103451732 citedByCount "29" @default.
- W2103451732 countsByYear W21034517322012 @default.
- W2103451732 countsByYear W21034517322013 @default.
- W2103451732 countsByYear W21034517322014 @default.
- W2103451732 countsByYear W21034517322015 @default.
- W2103451732 countsByYear W21034517322016 @default.
- W2103451732 countsByYear W21034517322017 @default.
- W2103451732 countsByYear W21034517322018 @default.
- W2103451732 countsByYear W21034517322019 @default.
- W2103451732 countsByYear W21034517322020 @default.
- W2103451732 countsByYear W21034517322021 @default.
- W2103451732 countsByYear W21034517322023 @default.
- W2103451732 crossrefType "journal-article" @default.
- W2103451732 hasAuthorship W2103451732A5088955577 @default.
- W2103451732 hasConcept C104317684 @default.
- W2103451732 hasConcept C159674089 @default.
- W2103451732 hasConcept C18903297 @default.
- W2103451732 hasConcept C203014093 @default.
- W2103451732 hasConcept C2779912340 @default.
- W2103451732 hasConcept C33594762 @default.
- W2103451732 hasConcept C55493867 @default.
- W2103451732 hasConcept C71924100 @default.
- W2103451732 hasConcept C86339819 @default.
- W2103451732 hasConcept C86803240 @default.
- W2103451732 hasConcept C8891405 @default.
- W2103451732 hasConceptScore W2103451732C104317684 @default.
- W2103451732 hasConceptScore W2103451732C159674089 @default.
- W2103451732 hasConceptScore W2103451732C18903297 @default.
- W2103451732 hasConceptScore W2103451732C203014093 @default.
- W2103451732 hasConceptScore W2103451732C2779912340 @default.
- W2103451732 hasConceptScore W2103451732C33594762 @default.
- W2103451732 hasConceptScore W2103451732C55493867 @default.
- W2103451732 hasConceptScore W2103451732C71924100 @default.
- W2103451732 hasConceptScore W2103451732C86339819 @default.
- W2103451732 hasConceptScore W2103451732C86803240 @default.
- W2103451732 hasConceptScore W2103451732C8891405 @default.
- W2103451732 hasIssue "2" @default.
- W2103451732 hasLocation W21034517321 @default.
- W2103451732 hasLocation W21034517322 @default.
- W2103451732 hasOpenAccess W2103451732 @default.
- W2103451732 hasPrimaryLocation W21034517321 @default.
- W2103451732 hasRelatedWork W2022689057 @default.
- W2103451732 hasRelatedWork W2103451732 @default.
- W2103451732 hasRelatedWork W2106999205 @default.
- W2103451732 hasRelatedWork W2108616261 @default.
- W2103451732 hasRelatedWork W2131198412 @default.
- W2103451732 hasRelatedWork W2420605253 @default.
- W2103451732 hasRelatedWork W2952842576 @default.
- W2103451732 hasRelatedWork W3187909465 @default.
- W2103451732 hasRelatedWork W4243623857 @default.
- W2103451732 hasRelatedWork W91094769 @default.
- W2103451732 hasVolume "40" @default.
- W2103451732 isParatext "false" @default.
- W2103451732 isRetracted "false" @default.
- W2103451732 magId "2103451732" @default.
- W2103451732 workType "article" @default.