FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103452253> ?p ?o ?g. }

• W2103452253 endingPage "20140619" @default.
• W2103452253 startingPage "20140619" @default.
• W2103452253 abstract "Evidence is accumulating that commonly used pesticides are linked to decline of pollinator populations; adverse effects of three neonicotinoids on bees have led to bans on their use across the European Union. Developing insecticides that pose negligible risks to beneficial organisms such as honeybees is desirable and timely. One strategy is to use recombinant fusion proteins containing neuroactive peptides/proteins linked to a ‘carrier’ protein that confers oral toxicity. Hv1a/GNA ( Galanthus nivalis agglutinin), containing an insect-specific spider venom calcium channel blocker (ω-hexatoxin-Hv1a) linked to snowdrop lectin (GNA) as a ‘carrier’, is an effective oral biopesticide towards various insect pests. Effects of Hv1a/GNA towards a non-target species, Apis mellifera , were assessed through a thorough early-tier risk assessment. Following feeding, honeybees internalized Hv1a/GNA, which reached the brain within 1 h after exposure. However, survival was only slightly affected by ingestion (LD 50 > 100 µg bee −1 ) or injection of fusion protein. Bees fed acute (100 µg bee −1 ) or chronic (0.35 mg ml −1 ) doses of Hv1a/GNA and trained in an olfactory learning task had similar rates of learning and memory to no-pesticide controls. Larvae were unaffected, being able to degrade Hv1a/GNA. These tests suggest that Hv1a/GNA is unlikely to cause detrimental effects on honeybees, indicating that atracotoxins targeting calcium channels are potential alternatives to conventional pesticides." @default.
• W2103452253 created "2016-06-24" @default.
• W2103452253 creator A5010501111 @default.
• W2103452253 creator A5032146711 @default.
• W2103452253 creator A5048722061 @default.
• W2103452253 creator A5051095628 @default.
• W2103452253 creator A5059621693 @default.
• W2103452253 creator A5065640824 @default.
• W2103452253 creator A5090115091 @default.
• W2103452253 date "2014-07-22" @default.
• W2103452253 modified "2023-10-15" @default.
• W2103452253 title "Novel biopesticide based on a spider venom peptide shows no adverse effects on honeybees" @default.
• W2103452253 cites W1656427482 @default.
• W2103452253 cites W1696872742 @default.
• W2103452253 cites W1736882089 @default.
• W2103452253 cites W1963871483 @default.
• W2103452253 cites W1967950590 @default.
• W2103452253 cites W1969644372 @default.
• W2103452253 cites W1986200189 @default.
• W2103452253 cites W1989574572 @default.
• W2103452253 cites W1991830886 @default.
• W2103452253 cites W1993051550 @default.
• W2103452253 cites W1994410010 @default.
• W2103452253 cites W2003734402 @default.
• W2103452253 cites W2011389888 @default.
• W2103452253 cites W2016541541 @default.
• W2103452253 cites W2023079974 @default.
• W2103452253 cites W2035759078 @default.
• W2103452253 cites W2037824587 @default.
• W2103452253 cites W2038054029 @default.
• W2103452253 cites W2046364225 @default.
• W2103452253 cites W2051890594 @default.
• W2103452253 cites W2051894831 @default.
• W2103452253 cites W2055225004 @default.
• W2103452253 cites W2066324317 @default.
• W2103452253 cites W2077894786 @default.
• W2103452253 cites W2085849969 @default.
• W2103452253 cites W2098498259 @default.
• W2103452253 cites W2099150972 @default.
• W2103452253 cites W2106668877 @default.
• W2103452253 cites W2120094218 @default.
• W2103452253 cites W2123036062 @default.
• W2103452253 cites W2123548738 @default.
• W2103452253 cites W2124395110 @default.
• W2103452253 cites W2145980235 @default.
• W2103452253 cites W2146084177 @default.
• W2103452253 cites W2148563040 @default.
• W2103452253 cites W2148845608 @default.
• W2103452253 cites W2158005028 @default.
• W2103452253 cites W4214713540 @default.
• W2103452253 doi "https://doi.org/10.1098/rspb.2014.0619" @default.
• W2103452253 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4071547" @default.
• W2103452253 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24898372" @default.
• W2103452253 hasPublicationYear "2014" @default.
• W2103452253 type Work @default.
• W2103452253 sameAs 2103452253 @default.
• W2103452253 citedByCount "42" @default.
• W2103452253 countsByYear W21034522532014 @default.
• W2103452253 countsByYear W21034522532015 @default.
• W2103452253 countsByYear W21034522532016 @default.
• W2103452253 countsByYear W21034522532017 @default.
• W2103452253 countsByYear W21034522532018 @default.
• W2103452253 countsByYear W21034522532019 @default.
• W2103452253 countsByYear W21034522532020 @default.
• W2103452253 countsByYear W21034522532021 @default.
• W2103452253 countsByYear W21034522532022 @default.
• W2103452253 countsByYear W21034522532023 @default.
• W2103452253 crossrefType "journal-article" @default.
• W2103452253 hasAuthorship W2103452253A5010501111 @default.
• W2103452253 hasAuthorship W2103452253A5032146711 @default.
• W2103452253 hasAuthorship W2103452253A5048722061 @default.
• W2103452253 hasAuthorship W2103452253A5051095628 @default.
• W2103452253 hasAuthorship W2103452253A5059621693 @default.
• W2103452253 hasAuthorship W2103452253A5065640824 @default.
• W2103452253 hasAuthorship W2103452253A5090115091 @default.
• W2103452253 hasBestOaLocation W21034522531 @default.
• W2103452253 hasConcept C120835403 @default.
• W2103452253 hasConcept C161176658 @default.
• W2103452253 hasConcept C18903297 @default.
• W2103452253 hasConcept C2776690007 @default.
• W2103452253 hasConcept C2777907900 @default.
• W2103452253 hasConcept C2779448229 @default.
• W2103452253 hasConcept C33070731 @default.
• W2103452253 hasConcept C55493867 @default.
• W2103452253 hasConcept C59822182 @default.
• W2103452253 hasConcept C84699730 @default.
• W2103452253 hasConcept C86803240 @default.
• W2103452253 hasConcept C90856448 @default.
• W2103452253 hasConcept C98274493 @default.
• W2103452253 hasConceptScore W2103452253C120835403 @default.
• W2103452253 hasConceptScore W2103452253C161176658 @default.
• W2103452253 hasConceptScore W2103452253C18903297 @default.
• W2103452253 hasConceptScore W2103452253C2776690007 @default.
• W2103452253 hasConceptScore W2103452253C2777907900 @default.
• W2103452253 hasConceptScore W2103452253C2779448229 @default.
• W2103452253 hasConceptScore W2103452253C33070731 @default.
• W2103452253 hasConceptScore W2103452253C55493867 @default.
• W2103452253 hasConceptScore W2103452253C59822182 @default.

• next