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• W2103455274 abstract "Investigate if patients with supraspinal lesions have impaired interlimb spinal reflex pathways. The short-latency crossed spinal response will be investigated during sitting from the non-paretic to paretic and paretic to non-paretic extremities at different stimulation intensities in chronic and sub-acute stroke patients. The ipsilateral tibial nerve of the paretic and non-paretic extremities were stimulated at motor threshold, 35% M-max and 85% M-max of the ipsilateral soleus while the contralateral soleus was contracted from 5% to 15% of the maximum voluntary contraction of the paretic soleus. Chronic patients (from both extremities) had significantly less prominent inhibitory responses than healthy controls (post hoc tests: P < .01–P < .05). The responses were significantly modulated by stimulus intensity in healthy controls and chronic patients (P < .001–P < .05) but not sub-acute patients (P > .05). Some sub-acute patients had significantly more variable responses than chronic patients and healthy controls (P < .001–P ⩽ .05). Short-latency interlimb reflexes are impaired differently in sub-acute vs. chronic patients, are impaired from the non-paretic and paretic extremity, and abnormal when compared to healthy controls. The inappropriate coordination could result in an inability to quickly avoid obstacles following a mechanical disturbance to the ipsilateral extremity. It also indicates that bilateral descending projections affect the response." @default.
• W2103455274 created "2016-06-24" @default.
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• W2103455274 date "2012-03-01" @default.
• W2103455274 modified "2023-10-15" @default.
• W2103455274 title "Short-latency crossed spinal responses are impaired differently in sub-acute and chronic stroke patients" @default.
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• W2103455274 doi "https://doi.org/10.1016/j.clinph.2011.07.033" @default.
• W2103455274 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21839674" @default.
• W2103455274 hasPublicationYear "2012" @default.
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