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• W2103459634 endingPage "947" @default.
• W2103459634 startingPage "937" @default.
• W2103459634 abstract "The availability of complete genome sequences from numerous organisms has provided investigators with the challenge of assigning physiologic functions to the encoded gene products. To facilitate this process, multiple technologies have been developed to profile the transcriptome and the proteome, including methods to monitor the function of enzymes in complex biologic systems. These methods typically target specific classes of enzymes and attempt to correlate the enzymatic activity with the specific phenotype of interest. Here, technologies to measure enzymatic activity on a subproteomic scale are reviewed, including the authors' own efforts, which are based on self-assembled microarrays utilizing peptide nucleic acid-encoded small-molecule libraries." @default.
• W2103459634 created "2016-06-24" @default.
• W2103459634 creator A5053671693 @default.
• W2103459634 creator A5071010224 @default.
• W2103459634 date "2005-12-01" @default.
• W2103459634 modified "2023-09-24" @default.
• W2103459634 title "Microarray-based functional protein profiling using peptide nucleic acid-encoded libraries" @default.
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• W2103459634 doi "https://doi.org/10.1586/14789450.2.6.937" @default.
• W2103459634 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16307522" @default.
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