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- W2103473411 abstract "Streptococcal mitogenic exotoxin Z (SMEZ), a superantigen derived from Streptococcus pyogenes, provoked expansion of human lymphocytes expressing the Vbeta 2, 4, 7 and 8 motifs of T-cell receptor. SMEZ was pyrogenic in rabbits and stimulated the expression of the T-cell activation markers CD69 and cutaneous lymphocyte-associated antigen. A variety of cytokines was released by human mononuclear leukocytes stimulated with SMEZ, which was 10-fold more active than streptococcal pyrogenic exotoxin A. Th2-derived cytokines were elicited only by superantigens and not by streptococcal cells." @default.
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- W2103473411 date "2001-06-01" @default.
- W2103473411 modified "2023-09-26" @default.
- W2103473411 title "Pyrogenicity and Cytokine-Inducing Properties of <i>Streptococcus pyogenes</i> Superantigens: Comparative Study of Streptococcal Mitogenic Exotoxin Z and Pyrogenic Exotoxin A" @default.
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- W2103473411 doi "https://doi.org/10.1128/iai.69.6.4141-4145.2001" @default.
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