FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103496411> ?p ?o ?g. }

• W2103496411 endingPage "1951" @default.
• W2103496411 startingPage "1936" @default.
• W2103496411 abstract "Abstract Chikungunya infection is a major disease of public health concern. The recurrent outbreaks of this viral disease and its progressive evolution demands a potential strategy to understand major aspects of its pathogenesis. Unlike other alphaviruses, Chikungunya virus (CHIKV) pathogenesis is poorly understood. In every consecutive outbreak, some new symptoms associated with virulence and disease manifestations are being reported such as neurological implication, increased severity and enhanced vector competence. In order to unravel the mechanism of the disease process, proteomic analysis was performed to evaluate the host response in CHIKV‐infected mice tissues. Comparative analysis of the multiple gels representing the particular tissue extract from mock and CHIKV‐infected tissues revealed a drastic reprogramming of physiological conditions through 35 and 15 differentially expressed proteins belonging to different classes such as stress, inflammation, apoptosis, urea cycle, energy metabolism, etc. from liver and brain, respectively. Based on the alterations obtained in the CHIKV mouse model, most of the aspects of CHIKV infection such as disease severity, neurological complications, disease susceptibility and immunocompetence could be defined. This is the first report unravelling the complicated pathways involved in the mechanism of Chikungunya disease pathogenesis employing proteomic approach." @default.
• W2103496411 created "2016-06-24" @default.
• W2103496411 creator A5040754239 @default.
• W2103496411 creator A5040776132 @default.
• W2103496411 creator A5046668061 @default.
• W2103496411 creator A5066381995 @default.
• W2103496411 creator A5077060611 @default.
• W2103496411 date "2011-04-07" @default.
• W2103496411 modified "2023-10-18" @default.
• W2103496411 title "Differential proteome analysis of Chikungunya virus-infected new-born mice tissues reveal implication of stress, inflammatory and apoptotic pathways in disease pathogenesis" @default.
• W2103496411 cites W1574201035 @default.
• W2103496411 cites W191793640 @default.
• W2103496411 cites W1918934150 @default.
• W2103496411 cites W1965572078 @default.
• W2103496411 cites W1971242896 @default.
• W2103496411 cites W1972125983 @default.
• W2103496411 cites W1973129732 @default.
• W2103496411 cites W1977349899 @default.
• W2103496411 cites W1986003731 @default.
• W2103496411 cites W1988256009 @default.
• W2103496411 cites W1993712001 @default.
• W2103496411 cites W1995237865 @default.
• W2103496411 cites W2014848125 @default.
• W2103496411 cites W2023314253 @default.
• W2103496411 cites W2023472561 @default.
• W2103496411 cites W2029370948 @default.
• W2103496411 cites W2038180816 @default.
• W2103496411 cites W2056929363 @default.
• W2103496411 cites W2059373490 @default.
• W2103496411 cites W2068012691 @default.
• W2103496411 cites W2073218335 @default.
• W2103496411 cites W2077475747 @default.
• W2103496411 cites W2099819774 @default.
• W2103496411 cites W2103900038 @default.
• W2103496411 cites W2106364045 @default.
• W2103496411 cites W2107277218 @default.
• W2103496411 cites W2133662129 @default.
• W2103496411 cites W2137626431 @default.
• W2103496411 cites W2148135345 @default.
• W2103496411 cites W2148673304 @default.
• W2103496411 cites W2149741097 @default.
• W2103496411 cites W2155906523 @default.
• W2103496411 cites W2467158718 @default.
• W2103496411 cites W4320800933 @default.
• W2103496411 doi "https://doi.org/10.1002/pmic.201000500" @default.
• W2103496411 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21472854" @default.
• W2103496411 hasPublicationYear "2011" @default.
• W2103496411 type Work @default.
• W2103496411 sameAs 2103496411 @default.
• W2103496411 citedByCount "57" @default.
• W2103496411 countsByYear W21034964112012 @default.
• W2103496411 countsByYear W21034964112013 @default.
• W2103496411 countsByYear W21034964112014 @default.
• W2103496411 countsByYear W21034964112015 @default.
• W2103496411 countsByYear W21034964112016 @default.
• W2103496411 countsByYear W21034964112017 @default.
• W2103496411 countsByYear W21034964112018 @default.
• W2103496411 countsByYear W21034964112019 @default.
• W2103496411 countsByYear W21034964112020 @default.
• W2103496411 countsByYear W21034964112022 @default.
• W2103496411 countsByYear W21034964112023 @default.
• W2103496411 crossrefType "journal-article" @default.
• W2103496411 hasAuthorship W2103496411A5040754239 @default.
• W2103496411 hasAuthorship W2103496411A5040776132 @default.
• W2103496411 hasAuthorship W2103496411A5046668061 @default.
• W2103496411 hasAuthorship W2103496411A5066381995 @default.
• W2103496411 hasAuthorship W2103496411A5077060611 @default.
• W2103496411 hasConcept C104317684 @default.
• W2103496411 hasConcept C104397665 @default.
• W2103496411 hasConcept C140704245 @default.
• W2103496411 hasConcept C140933497 @default.
• W2103496411 hasConcept C142724271 @default.
• W2103496411 hasConcept C159047783 @default.
• W2103496411 hasConcept C190283241 @default.
• W2103496411 hasConcept C203014093 @default.
• W2103496411 hasConcept C2522874641 @default.
• W2103496411 hasConcept C2776914184 @default.
• W2103496411 hasConcept C2779134260 @default.
• W2103496411 hasConcept C2780942790 @default.
• W2103496411 hasConcept C2781273456 @default.
• W2103496411 hasConcept C54355233 @default.
• W2103496411 hasConcept C60644358 @default.
• W2103496411 hasConcept C60987743 @default.
• W2103496411 hasConcept C71924100 @default.
• W2103496411 hasConcept C86803240 @default.
• W2103496411 hasConceptScore W2103496411C104317684 @default.
• W2103496411 hasConceptScore W2103496411C104397665 @default.
• W2103496411 hasConceptScore W2103496411C140704245 @default.
• W2103496411 hasConceptScore W2103496411C140933497 @default.
• W2103496411 hasConceptScore W2103496411C142724271 @default.
• W2103496411 hasConceptScore W2103496411C159047783 @default.
• W2103496411 hasConceptScore W2103496411C190283241 @default.
• W2103496411 hasConceptScore W2103496411C203014093 @default.
• W2103496411 hasConceptScore W2103496411C2522874641 @default.
• W2103496411 hasConceptScore W2103496411C2776914184 @default.
• W2103496411 hasConceptScore W2103496411C2779134260 @default.
• W2103496411 hasConceptScore W2103496411C2780942790 @default.
• W2103496411 hasConceptScore W2103496411C2781273456 @default.

• next