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- W2103510214 abstract "Introduction: D-dimer is present in elevated levels with different diseases. In this study we aimed to determine if a high D-dimer cut-off value might increase its specificity for the diagnosis of venous thromboembolism.Materials and methods: Retrospective analysis was carried out on 136 patients with a D-dimer value ≥ 8000 ng/ml.Results: 53 were diagnosed of VTE by objective methods (40%), and 65 were excluded from VTE diagnosis (49%). The final diagnoses for the patients excluded from VTE were: infections (n=23), cardiovascular diseases (n=14), fractures/traumas (n=12), disseminated malignancy (n=5), brain disease (n=5), and others (n=6). 30 patients died whilst hospitalized (23%). There were 6 deaths among the patients diagnosed with VTE (11%) and 20 among the patients excluded from VTE (31%) (p<0.01).Conclusions: A D-dimer threshold >8000 ng/mL is not specific to diagnose VTE. Patients with a D-dimer value >8000 ng/mL have a significantly worse prognosis when VTE is excluded by objective methods." @default.
- W2103510214 created "2016-06-24" @default.
- W2103510214 creator A5025659158 @default.
- W2103510214 date "2014-01-01" @default.
- W2103510214 modified "2023-09-26" @default.
- W2103510214 title "D-Dimer Specificity for the Diagnosis of Acute Symptomatic Pulmonary Embolism" @default.
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- W2103510214 doi "https://doi.org/10.4172/2329-8790.1000177" @default.
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