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- W2103524154 abstract "Bezafibrate (2,4,2-(4-chlorobenzamido)-ethyl-phenoxy-2-methylpropionic acid) has been shown to be an effective lipid-lowering drug in different types of hyperlipoproteinaemia, when administered at a dose of 200 mg three times a day (Gavish et al. 1986). Recently, a sustained-release form of Bezafibrate (400 mg tablet) has been introduced in order to improve patient’s compliance, due to the single daily dose which has to be taken. This sustained-release preparation, in comparison to the conventional form at the same dosage, is characterized by a similar relative biological availability (Ledermann and Kaufmann 1981), by a lower plasma peak concentration (34%), by a longer mean retention time (6.0 vs 2.4 h) and elimination half-life (2.6 vs 1.6 h) (Von Mollendorff 1984)." @default.
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- W2103524154 date "1987-01-01" @default.
- W2103524154 modified "2023-09-25" @default.
- W2103524154 title "Lipoprotein Changes Induced by Bezafibrate — 200 mg t. i. d. — and by Bezafibrate in a Slow-Release Preparation — 400 mg Once a Day — in Patients with Primary Hyperlipoproteinaemia" @default.
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- W2103524154 doi "https://doi.org/10.1007/978-3-642-71702-4_53" @default.
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