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- W2103530629 abstract "The deprotection of the tert-butyl group of a ferrocenyl uracil Peptide Nucleic Acid (PNA) monomer, Fmoc-aeg(R)-OtBu (1) was achieved using a two step synthesis involving hydrolysis in basic conditions to give first the zwitterion of +NH3-aeg(R)-O− (7). Compound 7 was reacted in situ with N-(9-fluorenylmethoxycarbonyloxy)succinimide to obtain the expected compound Fmoc-aeg(R)-OH (2) (Abbreviations: Aeg = (2-aminoethyl)-glycine; Fmoc = 9-fluorenylmethoxycarbonyl; OtBu = tert-butyl; R = 5-(N-ferroce-nylmethylbenzamido)uracyl)." @default.
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- W2103530629 date "2008-07-01" @default.
- W2103530629 modified "2023-10-17" @default.
- W2103530629 title "Synthesis of a ferrocenyl uracil PNA monomer for insertion into PNA sequences" @default.
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- W2103530629 doi "https://doi.org/10.1016/j.jorganchem.2008.05.009" @default.
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