Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103533676> ?p ?o ?g. }
- W2103533676 endingPage "78" @default.
- W2103533676 startingPage "69" @default.
- W2103533676 abstract "A global picture of gene expression in the common immune-mediated skin disease, psoriasis, was obtained by interrogating the full set of Affymetrix GeneChips with psoriatic and control skin samples. We identified 1,338 genes with potential roles in psoriasis pathogenesis/maintenance and revealed many perturbed biological processes. A novel method for identifying transcription factor binding sites was also developed and applied to this dataset. Many of the identified sites are known to be involved in immune response and proliferation. An in-depth study of immune system genes revealed the presence of many regulating cytokines and chemokines within involved skin, and markers of dendritic cell (DC) activation in uninvolved skin. The combination of many CCR7+ T cells, DCs, and regulating chemokines in psoriatic lesions, together with the detection of DC activation markers in nonlesional skin, strongly suggests that the spatial organization of T cells and DCs could sustain chronic T-cell activation and persistence within focal skin regions." @default.
- W2103533676 created "2016-06-24" @default.
- W2103533676 creator A5002970137 @default.
- W2103533676 creator A5008635035 @default.
- W2103533676 creator A5012790096 @default.
- W2103533676 creator A5015401462 @default.
- W2103533676 creator A5034410372 @default.
- W2103533676 creator A5050577808 @default.
- W2103533676 creator A5075798284 @default.
- W2103533676 creator A5080337749 @default.
- W2103533676 date "2003-03-18" @default.
- W2103533676 modified "2023-10-18" @default.
- W2103533676 title "Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array" @default.
- W2103533676 cites W1918229896 @default.
- W2103533676 cites W1962875376 @default.
- W2103533676 cites W1968699828 @default.
- W2103533676 cites W1976494868 @default.
- W2103533676 cites W1979085268 @default.
- W2103533676 cites W2002774826 @default.
- W2103533676 cites W2007990425 @default.
- W2103533676 cites W2009680323 @default.
- W2103533676 cites W2012194172 @default.
- W2103533676 cites W2013888332 @default.
- W2103533676 cites W2017345251 @default.
- W2103533676 cites W2020319641 @default.
- W2103533676 cites W2023815620 @default.
- W2103533676 cites W2024699319 @default.
- W2103533676 cites W2026168151 @default.
- W2103533676 cites W2033275545 @default.
- W2103533676 cites W2034095218 @default.
- W2103533676 cites W2035093405 @default.
- W2103533676 cites W2038437697 @default.
- W2103533676 cites W2046265070 @default.
- W2103533676 cites W2048532572 @default.
- W2103533676 cites W2050768623 @default.
- W2103533676 cites W2057240156 @default.
- W2103533676 cites W2072794124 @default.
- W2103533676 cites W2079732145 @default.
- W2103533676 cites W2081905124 @default.
- W2103533676 cites W2100533133 @default.
- W2103533676 cites W2104152486 @default.
- W2103533676 cites W210641201 @default.
- W2103533676 cites W2124567340 @default.
- W2103533676 cites W2131136878 @default.
- W2103533676 cites W2134326405 @default.
- W2103533676 cites W2149335113 @default.
- W2103533676 cites W2150926065 @default.
- W2103533676 cites W2163361020 @default.
- W2103533676 cites W2417916461 @default.
- W2103533676 cites W317225227 @default.
- W2103533676 cites W97469372 @default.
- W2103533676 cites W4323053706 @default.
- W2103533676 doi "https://doi.org/10.1152/physiolgenomics.00157.2002" @default.
- W2103533676 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12644634" @default.
- W2103533676 hasPublicationYear "2003" @default.
- W2103533676 type Work @default.
- W2103533676 sameAs 2103533676 @default.
- W2103533676 citedByCount "284" @default.
- W2103533676 countsByYear W21035336762012 @default.
- W2103533676 countsByYear W21035336762013 @default.
- W2103533676 countsByYear W21035336762014 @default.
- W2103533676 countsByYear W21035336762015 @default.
- W2103533676 countsByYear W21035336762016 @default.
- W2103533676 countsByYear W21035336762017 @default.
- W2103533676 countsByYear W21035336762018 @default.
- W2103533676 countsByYear W21035336762019 @default.
- W2103533676 countsByYear W21035336762020 @default.
- W2103533676 countsByYear W21035336762021 @default.
- W2103533676 countsByYear W21035336762022 @default.
- W2103533676 countsByYear W21035336762023 @default.
- W2103533676 crossrefType "journal-article" @default.
- W2103533676 hasAuthorship W2103533676A5002970137 @default.
- W2103533676 hasAuthorship W2103533676A5008635035 @default.
- W2103533676 hasAuthorship W2103533676A5012790096 @default.
- W2103533676 hasAuthorship W2103533676A5015401462 @default.
- W2103533676 hasAuthorship W2103533676A5034410372 @default.
- W2103533676 hasAuthorship W2103533676A5050577808 @default.
- W2103533676 hasAuthorship W2103533676A5075798284 @default.
- W2103533676 hasAuthorship W2103533676A5080337749 @default.
- W2103533676 hasConcept C127801297 @default.
- W2103533676 hasConcept C12823836 @default.
- W2103533676 hasConcept C13373296 @default.
- W2103533676 hasConcept C203014093 @default.
- W2103533676 hasConcept C2776090121 @default.
- W2103533676 hasConcept C2778170410 @default.
- W2103533676 hasConcept C2780564577 @default.
- W2103533676 hasConcept C86803240 @default.
- W2103533676 hasConcept C8891405 @default.
- W2103533676 hasConcept C95444343 @default.
- W2103533676 hasConceptScore W2103533676C127801297 @default.
- W2103533676 hasConceptScore W2103533676C12823836 @default.
- W2103533676 hasConceptScore W2103533676C13373296 @default.
- W2103533676 hasConceptScore W2103533676C203014093 @default.
- W2103533676 hasConceptScore W2103533676C2776090121 @default.
- W2103533676 hasConceptScore W2103533676C2778170410 @default.
- W2103533676 hasConceptScore W2103533676C2780564577 @default.
- W2103533676 hasConceptScore W2103533676C86803240 @default.
- W2103533676 hasConceptScore W2103533676C8891405 @default.