FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103536675> ?p ?o ?g. }

• W2103536675 endingPage "4026" @default.
• W2103536675 startingPage "4017" @default.
• W2103536675 abstract "The entry of methanol into the methylotrophic pathway of methanogenesis is mediated by the concerted effort of two methyltransferases, namely, methyltransferase 1 (MT1) and methyltransferase 2 (MT2). The mtaA1, mtaA2, and mtbA genes of Methanosarcina acetivorans C2A encode putative methanol- or methylamine-specific MT2 enzymes. To address the in vivo roles of these genes in growth and methanogenesis from known substrates, we constructed and characterized mutants with deletions of each of these genes. The mtaA1 gene is required for growth on methanol, whereas mtaA2 was dispensable. However, the mtaA2 mutant had a reduced rate of methane production from methanol. Surprisingly, deletion of mtaA1 in combination with deletions of the genes encoding three methanol-specific MT1 isozymes led to lack of growth on acetate, suggesting that MT1 and MT2 enzymes might play an important role during growth on this substrate. The mtbA gene was required for dimethylamine and monomethylamine (MMA) utilization and was important, but not required, for trimethylamine utilization. Analysis of reporter gene fusions revealed that both mtaA1 and mtbA were expressed on all methanogenic substrates tested. However, mtaA1 expression was induced on methanol, while mtbA expression was down-regulated on MMA and acetate. mtaA2 was expressed at very low levels on all substrates. The mtaA1 transcript had a large 5' untranslated region (UTR) (275 bp), while the 5' UTR of the mtbA transcript was only 28 bp long." @default.
• W2103536675 created "2016-06-24" @default.
• W2103536675 creator A5037791896 @default.
• W2103536675 creator A5088534913 @default.
• W2103536675 creator A5090435911 @default.
• W2103536675 date "2008-06-01" @default.
• W2103536675 modified "2023-09-25" @default.
• W2103536675 title "Genetic Analysis of the Methanol- and Methylamine-Specific Methyltransferase 2 Genes of <i>Methanosarcina acetivorans</i> C2A" @default.
• W2103536675 cites W1521026265 @default.
• W2103536675 cites W1549897988 @default.
• W2103536675 cites W1562902928 @default.
• W2103536675 cites W1565461456 @default.
• W2103536675 cites W1575831041 @default.
• W2103536675 cites W1615293143 @default.
• W2103536675 cites W1787690277 @default.
• W2103536675 cites W1965462740 @default.
• W2103536675 cites W1979583850 @default.
• W2103536675 cites W1980672599 @default.
• W2103536675 cites W1982101899 @default.
• W2103536675 cites W2010289128 @default.
• W2103536675 cites W2021414848 @default.
• W2103536675 cites W2022916467 @default.
• W2103536675 cites W2024884021 @default.
• W2103536675 cites W2037080719 @default.
• W2103536675 cites W2038804719 @default.
• W2103536675 cites W2047304632 @default.
• W2103536675 cites W2063016937 @default.
• W2103536675 cites W2064918826 @default.
• W2103536675 cites W2074384878 @default.
• W2103536675 cites W2096283831 @default.
• W2103536675 cites W2106882534 @default.
• W2103536675 cites W2115901152 @default.
• W2103536675 cites W2119148412 @default.
• W2103536675 cites W2119191909 @default.
• W2103536675 cites W2126838447 @default.
• W2103536675 cites W2130521343 @default.
• W2103536675 cites W2136993222 @default.
• W2103536675 cites W2140860400 @default.
• W2103536675 cites W2148090422 @default.
• W2103536675 cites W2149534614 @default.
• W2103536675 cites W2153223562 @default.
• W2103536675 cites W2158491612 @default.
• W2103536675 cites W2158954444 @default.
• W2103536675 cites W2162601736 @default.
• W2103536675 cites W2170124846 @default.
• W2103536675 cites W2797910473 @default.
• W2103536675 cites W4251095749 @default.
• W2103536675 doi "https://doi.org/10.1128/jb.00117-08" @default.
• W2103536675 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2395032" @default.
• W2103536675 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18375552" @default.
• W2103536675 hasPublicationYear "2008" @default.
• W2103536675 type Work @default.
• W2103536675 sameAs 2103536675 @default.
• W2103536675 citedByCount "35" @default.
• W2103536675 countsByYear W21035366752012 @default.
• W2103536675 countsByYear W21035366752013 @default.
• W2103536675 countsByYear W21035366752014 @default.
• W2103536675 countsByYear W21035366752015 @default.
• W2103536675 countsByYear W21035366752016 @default.
• W2103536675 countsByYear W21035366752017 @default.
• W2103536675 countsByYear W21035366752018 @default.
• W2103536675 countsByYear W21035366752019 @default.
• W2103536675 countsByYear W21035366752020 @default.
• W2103536675 countsByYear W21035366752021 @default.
• W2103536675 countsByYear W21035366752023 @default.
• W2103536675 crossrefType "journal-article" @default.
• W2103536675 hasAuthorship W2103536675A5037791896 @default.
• W2103536675 hasAuthorship W2103536675A5088534913 @default.
• W2103536675 hasAuthorship W2103536675A5090435911 @default.
• W2103536675 hasBestOaLocation W21035366752 @default.
• W2103536675 hasConcept C104317684 @default.
• W2103536675 hasConcept C143065580 @default.
• W2103536675 hasConcept C153911025 @default.
• W2103536675 hasConcept C2778563749 @default.
• W2103536675 hasConcept C2778589620 @default.
• W2103536675 hasConcept C2778969155 @default.
• W2103536675 hasConcept C33288867 @default.
• W2103536675 hasConcept C523546767 @default.
• W2103536675 hasConcept C54355233 @default.
• W2103536675 hasConcept C550995028 @default.
• W2103536675 hasConcept C55493867 @default.
• W2103536675 hasConcept C86803240 @default.
• W2103536675 hasConcept C91965660 @default.
• W2103536675 hasConceptScore W2103536675C104317684 @default.
• W2103536675 hasConceptScore W2103536675C143065580 @default.
• W2103536675 hasConceptScore W2103536675C153911025 @default.
• W2103536675 hasConceptScore W2103536675C2778563749 @default.
• W2103536675 hasConceptScore W2103536675C2778589620 @default.
• W2103536675 hasConceptScore W2103536675C2778969155 @default.
• W2103536675 hasConceptScore W2103536675C33288867 @default.
• W2103536675 hasConceptScore W2103536675C523546767 @default.
• W2103536675 hasConceptScore W2103536675C54355233 @default.
• W2103536675 hasConceptScore W2103536675C550995028 @default.
• W2103536675 hasConceptScore W2103536675C55493867 @default.
• W2103536675 hasConceptScore W2103536675C86803240 @default.
• W2103536675 hasConceptScore W2103536675C91965660 @default.
• W2103536675 hasIssue "11" @default.
• W2103536675 hasLocation W21035366751 @default.

• next