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• W2103552568 endingPage "2022" @default.
• W2103552568 startingPage "2013" @default.
• W2103552568 abstract "To investigate whether acute alcohol would affect performance of a conditioned behavioural response to obtain a reward outcome and impair performance in a task measuring inhibitory control to provide new knowledge of how the acute effects of alcohol might contribute to the transition from alcohol use to dependence.A randomized controlled between-subjects design was employed.The laboratory of experimental psychology at the University of Sussex.Thirty-two light to moderate social drinkers recruited from the undergraduate and postgraduate population.After the administration of alcohol (0.8 g/kg) or placebo participants underwent an instrumental reward-seeking procedure, with abstract stimuli serving as S+ (always predicting a win of 10 pence) and S- (always predicting a loss of 10 pence). In addition, a Stop Signal task was administered before and after the administration of alcohol.Participants of the alcohol group performed the behavioural response to obtain the reward outcome more often than placebo subjects in trials associated with loss of money. This finding was observed, although alcohol was not affecting explicit knowledge of stimulus-response outcome contingencies and acquisition of conditioned attentional and emotional responses. In addition, alcohol increased Stop Signal reaction time indicating disinhibiting effects of alcohol, and this was associated positively with response probability to the S-.These results demonstrate that alcohol is affecting inhibitory control of behavioural responses to external signals even when associated with punishment, contributing in this way to the transition from alcohol use to dependence." @default.
• W2103552568 created "2016-06-24" @default.
• W2103552568 creator A5049788792 @default.
• W2103552568 creator A5056097715 @default.
• W2103552568 date "2009-11-09" @default.
• W2103552568 modified "2023-10-16" @default.
• W2103552568 title "Acute alcohol impairs conditioning of a behavioural reward-seeking response and inhibitory control processes-implications for addictive disorders" @default.
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• W2103552568 doi "https://doi.org/10.1111/j.1360-0443.2009.02718.x" @default.
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