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- W2103553417 abstract "Chronic disseminated candidiasis (CDC) is a form of Candida species infection observed primarily in patients with acute leukemia. To investigate possible genetic factors associated with CDC, we conducted a pilot study of 40 patients with both leukemia and CDC and 50 control patients with leukemia only. A common haplotype of the IL4 promoter (−1098T/−589C/−33C) was overrepresented in patients with CDC (P=.01; odds ratio [OR], 2.16), whereas another common haplotype (−1098T/−589T/−33T) appeared to be protective against CDC (P=.018; OR, 0.47). Genetic variants of IL4 could contribute to the development of CDC in patients with acute leukemia" @default.
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- W2103553417 date "2003-04-01" @default.
- W2103553417 modified "2023-10-16" @default.
- W2103553417 title "Association between Chronic Disseminated Candidiasis in Adult Acute Leukemia and Common<i>IL4</i>Promoter Haplotypes" @default.
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- W2103553417 doi "https://doi.org/10.1086/368345" @default.
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