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- W2103607346 abstract "It was recently demonstrated that progestational steroids produced their characteristic biological effects even after topical application (Shipley, 1965; Ringler, 1966). However, a similar observation for non-steroidal antifertility agents has not been reported. U11555A (Duncan, Stucki, Lyster & Lednicer, 1962) and MRL-41 (Holtkamp, Greslin, Root & Lerner, 1960) were shown to be potent non-steroidal female contraceptives following oral or subcutaneous administration. These agents exerted their antifertility effect only when given before foetal implantation. The present investigation examined the efficacy of these compounds after topical application. Female rats of the Wistar strain (Royal Hart Colony), weighing approximately 250 g, were given free access to unlimited supplies of food and water, and housed in a controlled illumination environment of 14 hr light and 10 hr dark-" @default.
- W2103607346 created "2016-06-24" @default.
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- W2103607346 date "1967-04-01" @default.
- W2103607346 modified "2023-09-26" @default.
- W2103607346 title "THE EFFICACY OF TWO NON-STEROIDAL ANTIFERTILITY AGENTS AFTER TOPICAL ADMINISTRATION IN RATS" @default.
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- W2103607346 doi "https://doi.org/10.1530/jrf.0.0130373" @default.
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