FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103607778> ?p ?o ?g. }

• W2103607778 abstract "Articular cartilage (AC) is the layer of tissue that covers the articulating ends of the bones in diarthrodial joints. Across species, adult AC shows an arcade-like structure with collagen predominantly perpendicular to the subchondral bone near the bone, and collagen predominantly parallel to the articular surface near the articular surface. Recent studies into collagen fibre orientation in stillborn and juvenile animals showed that this structure is absent at birth. Since the collagen structure is an important factor for AC mechanics, the absence of the adult Benninghoff structure has implications for perinatal AC mechanobiology. The current objective is to quantify the dynamics of collagen network development in a model animal from birth to maturity. We further aim to show the presence or absence of zonal differentiation at birth, and to assess differences in collagen network development between different anatomical sites of a single joint surface. We use quantitative polarised light microscopy to investigate properties of the collagen network and we use the sheep (Ovis aries) as our model animal.Predominant collagen orientation is parallel to the articular surface throughout the tissue depth for perinatal cartilage. This remodels to the Benninghoff structure before the sheep reach sexual maturity. Remodelling of predominant collagen orientation starts at a depth just below the future transitional zone. Tissue retardance shows a minimum near the articular surface at all ages, which indicates the presence of zonal differentiation at all ages. The absolute position of this minimum does change between birth and maturity. Between different anatomical sites, we find differences in the dynamics of collagen remodelling, but no differences in adult collagen structure.The collagen network in articular cartilage remodels between birth and sexual maturity from a network with predominant orientation parallel to the articular surface to a Benninghoff network. The retardance minimum near, but not at, the articular surface at all ages shows that a zonal differentiation is already present in the perinatal animals. In these animals, the zonal differentiation can not be correlated to the collagen network orientation. We find no difference in adult collagen structure in the nearly congruent metacarpophalangeal joint, but we do find differences in the dynamics of collagen network remodelling." @default.
• W2103607778 created "2016-06-24" @default.
• W2103607778 creator A5011213215 @default.
• W2103607778 creator A5017772851 @default.
• W2103607778 creator A5019484533 @default.
• W2103607778 creator A5032409374 @default.
• W2103607778 creator A5036952147 @default.
• W2103607778 creator A5089278859 @default.
• W2103607778 date "2010-06-07" @default.
• W2103607778 modified "2023-09-27" @default.
• W2103607778 title "Postnatal development of collagen structure in ovine articular cartilage" @default.
• W2103607778 cites W1545577649 @default.
• W2103607778 cites W1968578768 @default.
• W2103607778 cites W1974069175 @default.
• W2103607778 cites W1981747359 @default.
• W2103607778 cites W1982120544 @default.
• W2103607778 cites W1986992340 @default.
• W2103607778 cites W1990292037 @default.
• W2103607778 cites W1990488312 @default.
• W2103607778 cites W1996204310 @default.
• W2103607778 cites W1999233071 @default.
• W2103607778 cites W2004304953 @default.
• W2103607778 cites W2006302083 @default.
• W2103607778 cites W2009264513 @default.
• W2103607778 cites W2009651788 @default.
• W2103607778 cites W2010358571 @default.
• W2103607778 cites W2010620072 @default.
• W2103607778 cites W2014464964 @default.
• W2103607778 cites W2018393167 @default.
• W2103607778 cites W2018674961 @default.
• W2103607778 cites W2025589190 @default.
• W2103607778 cites W2031569215 @default.
• W2103607778 cites W2034456995 @default.
• W2103607778 cites W2036856612 @default.
• W2103607778 cites W2037691979 @default.
• W2103607778 cites W2040249412 @default.
• W2103607778 cites W2043404062 @default.
• W2103607778 cites W2045307776 @default.
• W2103607778 cites W2045942656 @default.
• W2103607778 cites W2046212734 @default.
• W2103607778 cites W2048284505 @default.
• W2103607778 cites W2051666048 @default.
• W2103607778 cites W2052556118 @default.
• W2103607778 cites W2053279210 @default.
• W2103607778 cites W2055595178 @default.
• W2103607778 cites W2058721833 @default.
• W2103607778 cites W2060476700 @default.
• W2103607778 cites W2063405742 @default.
• W2103607778 cites W2065745947 @default.
• W2103607778 cites W2066330669 @default.
• W2103607778 cites W2068465457 @default.
• W2103607778 cites W2069187544 @default.
• W2103607778 cites W2069329799 @default.
• W2103607778 cites W2069455397 @default.
• W2103607778 cites W2076513735 @default.
• W2103607778 cites W2079377337 @default.
• W2103607778 cites W2083893071 @default.
• W2103607778 cites W2088752908 @default.
• W2103607778 cites W2089155230 @default.
• W2103607778 cites W2096939677 @default.
• W2103607778 cites W2105608275 @default.
• W2103607778 cites W2108927236 @default.
• W2103607778 cites W2109869002 @default.
• W2103607778 cites W2110806917 @default.
• W2103607778 cites W2113719591 @default.
• W2103607778 cites W2129375078 @default.
• W2103607778 cites W2134256482 @default.
• W2103607778 cites W2139368735 @default.
• W2103607778 cites W2144707232 @default.
• W2103607778 cites W2149100719 @default.
• W2103607778 cites W2163660740 @default.
• W2103607778 cites W236611178 @default.
• W2103607778 cites W2584544351 @default.
• W2103607778 cites W4244611409 @default.
• W2103607778 cites W4294344990 @default.
• W2103607778 cites W54795896 @default.
• W2103607778 doi "https://doi.org/10.1186/1471-213x-10-62" @default.
• W2103607778 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2906441" @default.
• W2103607778 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20529268" @default.
• W2103607778 hasPublicationYear "2010" @default.
• W2103607778 type Work @default.
• W2103607778 sameAs 2103607778 @default.
• W2103607778 citedByCount "41" @default.
• W2103607778 countsByYear W21036077782012 @default.
• W2103607778 countsByYear W21036077782013 @default.
• W2103607778 countsByYear W21036077782014 @default.
• W2103607778 countsByYear W21036077782015 @default.
• W2103607778 countsByYear W21036077782016 @default.
• W2103607778 countsByYear W21036077782017 @default.
• W2103607778 countsByYear W21036077782018 @default.
• W2103607778 countsByYear W21036077782020 @default.
• W2103607778 countsByYear W21036077782021 @default.
• W2103607778 countsByYear W21036077782022 @default.
• W2103607778 countsByYear W21036077782023 @default.
• W2103607778 crossrefType "journal-article" @default.
• W2103607778 hasAuthorship W2103607778A5011213215 @default.
• W2103607778 hasAuthorship W2103607778A5017772851 @default.
• W2103607778 hasAuthorship W2103607778A5019484533 @default.
• W2103607778 hasAuthorship W2103607778A5032409374 @default.
• W2103607778 hasAuthorship W2103607778A5036952147 @default.

• next