Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103642246> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2103642246 endingPage "132" @default.
- W2103642246 startingPage "127" @default.
- W2103642246 abstract "The halotolerant alga, D. salina, offsets the high (up to 5 M) external NaCl concentration in its environment by maintaining a nearly equivalent level of intracellular glycerol. Cells experiencing sudden hypoosmotic shock respond initially by volume expansion and then convert glycerol to osmotically inactive starch. Within 2 min following dilution of cells from 1.7 M NaCl to 0.85 M NaCl, their volume and surface area increase by 50%. Concurrently, the plasma membrane phosphatidylinositol 4,5-bisphosphate (PIP2) level falls by 30% due to hydrolysis by a GTP-binding, protein-activated phospholipase C that produces inositol trisphosphate and diacylglycerol (DAG). Following the short-lived rise of PIP2-derived DAG, a second and larger peak of DAG is produced by the hydrolysis of phosphatidylcholine and through de novo synthesis. Since protein kinase C is not detectably stimulated, DAG may act through the alternative pathway of increasing actin nucleation sites, thereby facilitating expansion of the cell's cytoskeleton. D. salina contains a family of at least 4 low molecular weight (28–30 kDa) GTP-binding proteins. The major one of these (28 kDa) is immunologically cross-reactive with antibodies to the yeast ypt1 protein that is involved in intracellular vesicle trafficking. The D. salina 28 kDa protein may play a similar role in facilitating the plasma membrane expansion triggered by hypoosmotic shock. During this expansion, which features a massive fusion of cytoplasmic vesicles with the plasma membrane, there is significant translocation of the 28 kDa GTP-binding protein from the ER-enriched microsomal fraction to the plasma membrane, chloroplast, and cytosol. Factors regulating these translocations are under study. © 1994 Wiley-Liss, Inc." @default.
- W2103642246 created "2016-06-24" @default.
- W2103642246 creator A5079082310 @default.
- W2103642246 date "1994-02-01" @default.
- W2103642246 modified "2023-09-27" @default.
- W2103642246 title "Mechanisms of osmoregulation in the green algaDunaliella salina" @default.
- W2103642246 cites W1533669901 @default.
- W2103642246 cites W1964690201 @default.
- W2103642246 cites W1967034069 @default.
- W2103642246 cites W1971265845 @default.
- W2103642246 cites W1978412017 @default.
- W2103642246 cites W1987696666 @default.
- W2103642246 cites W1998490733 @default.
- W2103642246 cites W2007057750 @default.
- W2103642246 cites W2017266574 @default.
- W2103642246 cites W2020403539 @default.
- W2103642246 cites W2036958086 @default.
- W2103642246 cites W2059428912 @default.
- W2103642246 cites W2060494176 @default.
- W2103642246 cites W2088043418 @default.
- W2103642246 cites W2151484207 @default.
- W2103642246 cites W2169345570 @default.
- W2103642246 cites W2281599944 @default.
- W2103642246 cites W2804275696 @default.
- W2103642246 cites W4211235955 @default.
- W2103642246 doi "https://doi.org/10.1002/jez.1402680209" @default.
- W2103642246 hasPublicationYear "1994" @default.
- W2103642246 type Work @default.
- W2103642246 sameAs 2103642246 @default.
- W2103642246 citedByCount "7" @default.
- W2103642246 countsByYear W21036422462017 @default.
- W2103642246 countsByYear W21036422462020 @default.
- W2103642246 crossrefType "journal-article" @default.
- W2103642246 hasAuthorship W2103642246A5079082310 @default.
- W2103642246 hasConcept C118716 @default.
- W2103642246 hasConcept C130316041 @default.
- W2103642246 hasConcept C181199279 @default.
- W2103642246 hasConcept C184235292 @default.
- W2103642246 hasConcept C185592680 @default.
- W2103642246 hasConcept C18903297 @default.
- W2103642246 hasConcept C195794163 @default.
- W2103642246 hasConcept C2778159673 @default.
- W2103642246 hasConcept C2780610907 @default.
- W2103642246 hasConcept C36020004 @default.
- W2103642246 hasConcept C41625074 @default.
- W2103642246 hasConcept C55493867 @default.
- W2103642246 hasConcept C559758991 @default.
- W2103642246 hasConcept C86803240 @default.
- W2103642246 hasConcept C95444343 @default.
- W2103642246 hasConcept C98539663 @default.
- W2103642246 hasConceptScore W2103642246C118716 @default.
- W2103642246 hasConceptScore W2103642246C130316041 @default.
- W2103642246 hasConceptScore W2103642246C181199279 @default.
- W2103642246 hasConceptScore W2103642246C184235292 @default.
- W2103642246 hasConceptScore W2103642246C185592680 @default.
- W2103642246 hasConceptScore W2103642246C18903297 @default.
- W2103642246 hasConceptScore W2103642246C195794163 @default.
- W2103642246 hasConceptScore W2103642246C2778159673 @default.
- W2103642246 hasConceptScore W2103642246C2780610907 @default.
- W2103642246 hasConceptScore W2103642246C36020004 @default.
- W2103642246 hasConceptScore W2103642246C41625074 @default.
- W2103642246 hasConceptScore W2103642246C55493867 @default.
- W2103642246 hasConceptScore W2103642246C559758991 @default.
- W2103642246 hasConceptScore W2103642246C86803240 @default.
- W2103642246 hasConceptScore W2103642246C95444343 @default.
- W2103642246 hasConceptScore W2103642246C98539663 @default.
- W2103642246 hasIssue "2" @default.
- W2103642246 hasLocation W21036422461 @default.
- W2103642246 hasOpenAccess W2103642246 @default.
- W2103642246 hasPrimaryLocation W21036422461 @default.
- W2103642246 hasRelatedWork W1974805430 @default.
- W2103642246 hasRelatedWork W1980179544 @default.
- W2103642246 hasRelatedWork W2006096146 @default.
- W2103642246 hasRelatedWork W2012858142 @default.
- W2103642246 hasRelatedWork W2032148392 @default.
- W2103642246 hasRelatedWork W2046880949 @default.
- W2103642246 hasRelatedWork W2072603692 @default.
- W2103642246 hasRelatedWork W2338359576 @default.
- W2103642246 hasRelatedWork W2339733063 @default.
- W2103642246 hasRelatedWork W298592923 @default.
- W2103642246 hasVolume "268" @default.
- W2103642246 isParatext "false" @default.
- W2103642246 isRetracted "false" @default.
- W2103642246 magId "2103642246" @default.
- W2103642246 workType "article" @default.