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• W2103666730 abstract "<para xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink> Magnetic particle tagging techniques are currently being applied to tissue engineering applications such as controlled differentiation of mesenchymal stem cells (MSC). In order to define key mechanotransducers underpinning these applications, the electrophysiological responses of human MSCs (hMSC) have been investigated. Ferromagnetic microparticles were coated with <formula formulatype=inline><tex Notation=TeX>${rm L}$</tex></formula>-arginyl-glycyl- <formula formulatype=inline><tex Notation=TeX>${rm L}$</tex></formula>-aspartic acid in order to target the application of dynamic force (6 pN) directly to cell surface integrins. Human MSCs demonstrated cell membrane hyperpolarization responses after the application of force, mediated by BK channels and intracellular calcium release. </para>" @default.
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• W2103666730 date "2010-03-01" @default.
• W2103666730 modified "2023-10-18" @default.
• W2103666730 title "Hyperpolarization of Human Mesenchymal Stem Cells in Response to Magnetic Force" @default.
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• W2103666730 doi "https://doi.org/10.1109/tnb.2010.2042065" @default.
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