FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2103667461> ?p ?o ?g. }

• W2103667461 endingPage "e3036" @default.
• W2103667461 startingPage "e3036" @default.
• W2103667461 abstract "There is conflicting evidence on the immunologic benefit of treating helminth co-infections (deworming) in HIV-infected individuals. Several studies have documented reduced viral load and increased CD4 count in antiretroviral therapy (ART) naïve individuals after deworming. However, there are a lack of data on the effect of deworming therapy on CD4 count recovery among HIV-infected persons taking ART.To estimate the association between empiric deworming therapy and CD4 count after ART initiation, we performed a retrospective observational study among HIV-infected adults on ART at a publicly operated HIV clinic in southwestern Uganda. Subjects were assigned as having received deworming if prescribed an anti-helminthic agent between 7 and 90 days before a CD4 test. To estimate the association between deworming and CD4 count, we fit multivariable regression models and analyzed predictors of CD4 count, using a time-by-interaction term with receipt or non-receipt of deworming. From 1998 to 2009, 5,379 subjects on ART attended 21,933 clinic visits at which a CD4 count was measured. Subjects received deworming prior to 668 (3%) visits. Overall, deworming was not associated with a significant difference in CD4 count in either the first year on ART (β = 42.8; 95% CI, -2.1 to 87.7) or after the first year of ART (β = -9.9; 95% CI, -24.1 to 4.4). However, in a sub-analysis by gender, during the first year of ART deworming was associated with a significantly greater rise in CD4 count (β = 63.0; 95% CI, 6.0 to 120.1) in females.Empiric deworming of HIV-infected individuals on ART conferred no significant generalized benefit on subsequent CD4 count recovery. A significant association was observed exclusively in females and during the initial year on ART. Our findings are consistent with recent studies that failed to demonstrate an immunologic advantage to empirically deworming ART-naïve individuals, but suggest that certain sub-populations may benefit." @default.
• W2103667461 created "2016-06-24" @default.
• W2103667461 creator A5003051495 @default.
• W2103667461 creator A5009636499 @default.
• W2103667461 creator A5025254769 @default.
• W2103667461 creator A5025935350 @default.
• W2103667461 creator A5028079153 @default.
• W2103667461 creator A5049741179 @default.
• W2103667461 creator A5065731602 @default.
• W2103667461 creator A5068769240 @default.
• W2103667461 creator A5073389592 @default.
• W2103667461 creator A5091101403 @default.
• W2103667461 date "2014-08-07" @default.
• W2103667461 modified "2023-10-06" @default.
• W2103667461 title "Empiric Deworming and CD4 Count Recovery in HIV-Infected Ugandans Initiating Antiretroviral Therapy" @default.
• W2103667461 cites W1497170016 @default.
• W2103667461 cites W1966193770 @default.
• W2103667461 cites W1967829982 @default.
• W2103667461 cites W1973508574 @default.
• W2103667461 cites W1975005043 @default.
• W2103667461 cites W1977797184 @default.
• W2103667461 cites W1978141065 @default.
• W2103667461 cites W1978864579 @default.
• W2103667461 cites W1980005248 @default.
• W2103667461 cites W1981367337 @default.
• W2103667461 cites W1982973492 @default.
• W2103667461 cites W1988963904 @default.
• W2103667461 cites W1997245469 @default.
• W2103667461 cites W1997739963 @default.
• W2103667461 cites W1998279724 @default.
• W2103667461 cites W2004047573 @default.
• W2103667461 cites W2009447956 @default.
• W2103667461 cites W2025897624 @default.
• W2103667461 cites W2036505093 @default.
• W2103667461 cites W2036735100 @default.
• W2103667461 cites W2046166857 @default.
• W2103667461 cites W2049539466 @default.
• W2103667461 cites W2056400914 @default.
• W2103667461 cites W2064586997 @default.
• W2103667461 cites W2076685189 @default.
• W2103667461 cites W2085938680 @default.
• W2103667461 cites W2086310869 @default.
• W2103667461 cites W2086511108 @default.
• W2103667461 cites W2087092404 @default.
• W2103667461 cites W2095760978 @default.
• W2103667461 cites W2095782528 @default.
• W2103667461 cites W2096690223 @default.
• W2103667461 cites W2097154172 @default.
• W2103667461 cites W2098152094 @default.
• W2103667461 cites W2101912413 @default.
• W2103667461 cites W2102201378 @default.
• W2103667461 cites W2106654454 @default.
• W2103667461 cites W2107108433 @default.
• W2103667461 cites W2108818539 @default.
• W2103667461 cites W2108859519 @default.
• W2103667461 cites W2109054861 @default.
• W2103667461 cites W2110712236 @default.
• W2103667461 cites W2112762036 @default.
• W2103667461 cites W2116169270 @default.
• W2103667461 cites W2118016322 @default.
• W2103667461 cites W2122483069 @default.
• W2103667461 cites W2122544370 @default.
• W2103667461 cites W2127274540 @default.
• W2103667461 cites W2134658102 @default.
• W2103667461 cites W2153136696 @default.
• W2103667461 cites W2156846423 @default.
• W2103667461 cites W2170138309 @default.
• W2103667461 cites W2187955543 @default.
• W2103667461 cites W4234297355 @default.
• W2103667461 doi "https://doi.org/10.1371/journal.pntd.0003036" @default.
• W2103667461 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4125278" @default.
• W2103667461 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25101890" @default.
• W2103667461 hasPublicationYear "2014" @default.
• W2103667461 type Work @default.
• W2103667461 sameAs 2103667461 @default.
• W2103667461 citedByCount "10" @default.
• W2103667461 countsByYear W21036674612015 @default.
• W2103667461 countsByYear W21036674612016 @default.
• W2103667461 countsByYear W21036674612017 @default.
• W2103667461 countsByYear W21036674612018 @default.
• W2103667461 countsByYear W21036674612019 @default.
• W2103667461 countsByYear W21036674612021 @default.
• W2103667461 countsByYear W21036674612023 @default.
• W2103667461 crossrefType "journal-article" @default.
• W2103667461 hasAuthorship W2103667461A5003051495 @default.
• W2103667461 hasAuthorship W2103667461A5009636499 @default.
• W2103667461 hasAuthorship W2103667461A5025254769 @default.
• W2103667461 hasAuthorship W2103667461A5025935350 @default.
• W2103667461 hasAuthorship W2103667461A5028079153 @default.
• W2103667461 hasAuthorship W2103667461A5049741179 @default.
• W2103667461 hasAuthorship W2103667461A5065731602 @default.
• W2103667461 hasAuthorship W2103667461A5068769240 @default.
• W2103667461 hasAuthorship W2103667461A5073389592 @default.
• W2103667461 hasAuthorship W2103667461A5091101403 @default.
• W2103667461 hasBestOaLocation W21036674611 @default.
• W2103667461 hasConcept C126322002 @default.
• W2103667461 hasConcept C142462285 @default.
• W2103667461 hasConcept C165901193 @default.

• next